Preemptive Use of Palliative Sedation and Amyotrophic Lateral Sclerosis
Abstract Patients in the advanced stages of amyotrophic lateral sclerosis often are faced with the dilemma of whether to use or continue to use mechanical ventilation. Patients who elect to terminate ventilatory support may be subject to significant and even extreme respiratory symptoms. Severe dysp...
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| Veröffentlicht in: | Journal of pain and symptom management 2012-04, Vol.43 (4), p.802-805 |
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| container_title | Journal of pain and symptom management |
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| creator | Berger, Jeffrey T., MD |
| description | Abstract Patients in the advanced stages of amyotrophic lateral sclerosis often are faced with the dilemma of whether to use or continue to use mechanical ventilation. Patients who elect to terminate ventilatory support may be subject to significant and even extreme respiratory symptoms. Severe dyspnea and other symptoms are sometimes treated with palliative sedation, which is generally recommended as a last resort approach to refractory symptoms. However, the preemptive use of palliative sedation is sometimes appropriate. The preemptive use of palliative sedation is examined through a case-based analysis of a patient with advanced amyotrophic lateral sclerosis. |
| doi_str_mv | 10.1016/j.jpainsymman.2011.10.012 |
| format | Article |
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Patients who elect to terminate ventilatory support may be subject to significant and even extreme respiratory symptoms. Severe dyspnea and other symptoms are sometimes treated with palliative sedation, which is generally recommended as a last resort approach to refractory symptoms. However, the preemptive use of palliative sedation is sometimes appropriate. The preemptive use of palliative sedation is examined through a case-based analysis of a patient with advanced amyotrophic lateral sclerosis.</description><identifier>ISSN: 0885-3924</identifier><identifier>EISSN: 1873-6513</identifier><identifier>DOI: 10.1016/j.jpainsymman.2011.10.012</identifier><identifier>PMID: 22464355</identifier><identifier>CODEN: JSPME2</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Amyotrophic lateral sclerosis ; Amyotrophic Lateral Sclerosis - complications ; Amyotrophic Lateral Sclerosis - therapy ; Anesthesia & Perioperative Care ; Artificial respiration ; Biological and medical sciences ; Cerebrospinal fluid. Meninges. Spinal cord ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Dyspnea - etiology ; Dyspnea - prevention & control ; Ethics ; Extremes ; Humans ; Hypnotics and Sedatives - therapeutic use ; Lorazepam - therapeutic use ; Male ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurology ; Pain Medicine ; Palliative care ; Palliative Care - methods ; palliative sedation ; Pharmacology. Drug treatments ; Sedation ; Symptoms ; Treatment Outcome</subject><ispartof>Journal of pain and symptom management, 2012-04, Vol.43 (4), p.802-805</ispartof><rights>U.S. Cancer Pain Relief Committee</rights><rights>2012 U.S. Cancer Pain Relief Committee</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2012 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c545t-224eb303ddb08497d48726862c10609d442da94f760c8468daa6e81a3bc3024e3</citedby><cites>FETCH-LOGICAL-c545t-224eb303ddb08497d48726862c10609d442da94f760c8468daa6e81a3bc3024e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jpainsymman.2011.10.012$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,31000,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25811946$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22464355$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Berger, Jeffrey T., MD</creatorcontrib><title>Preemptive Use of Palliative Sedation and Amyotrophic Lateral Sclerosis</title><title>Journal of pain and symptom management</title><addtitle>J Pain Symptom Manage</addtitle><description>Abstract Patients in the advanced stages of amyotrophic lateral sclerosis often are faced with the dilemma of whether to use or continue to use mechanical ventilation. Patients who elect to terminate ventilatory support may be subject to significant and even extreme respiratory symptoms. Severe dyspnea and other symptoms are sometimes treated with palliative sedation, which is generally recommended as a last resort approach to refractory symptoms. However, the preemptive use of palliative sedation is sometimes appropriate. The preemptive use of palliative sedation is examined through a case-based analysis of a patient with advanced amyotrophic lateral sclerosis.</description><subject>Adult</subject><subject>Amyotrophic lateral sclerosis</subject><subject>Amyotrophic Lateral Sclerosis - complications</subject><subject>Amyotrophic Lateral Sclerosis - therapy</subject><subject>Anesthesia & Perioperative Care</subject><subject>Artificial respiration</subject><subject>Biological and medical sciences</subject><subject>Cerebrospinal fluid. Meninges. Spinal cord</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>Dyspnea - etiology</subject><subject>Dyspnea - prevention & control</subject><subject>Ethics</subject><subject>Extremes</subject><subject>Humans</subject><subject>Hypnotics and Sedatives - therapeutic use</subject><subject>Lorazepam - therapeutic use</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Pain Medicine</subject><subject>Palliative care</subject><subject>Palliative Care - methods</subject><subject>palliative sedation</subject><subject>Pharmacology. Drug treatments</subject><subject>Sedation</subject><subject>Symptoms</subject><subject>Treatment Outcome</subject><issn>0885-3924</issn><issn>1873-6513</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqNkl9rFDEUxYModq1-BRkfpL7MNv8mm7wIZdFaWGhhLfgWsskdzJjJjMlsYb-9GXfV4oP4lHDzO_ckJxehNwQvCSbislt2o_ExH_rexCXFhJT6EhP6BC2IXLFaNIQ9RQssZVMzRfkZepFzhzFumGDP0RmlXHDWNAt0fZcA-nHyD1DdZ6iGtrozIXjzs7IFVzZDrEx01VV_GKY0jF-9rTZmgmRCtbUB0pB9fometSZkeHVaz9H9xw-f15_qze31zfpqU9uGN1NdjGHHMHNuhyVXK8fligopqCVYYOU4p84o3q4EtpIL6YwRIIlhO8tw0bJzdHHsO6bh-x7ypHufLYRgIgz7rJVgklGseCHf_ZMkmDKsiFK0oOqI2vKWnKDVY_K9SYcC6Tlx3elHies58fmoJF60r082-10P7rfyV8QFeHsCTLYmtMlE6_MfrpGEKC4Ktz5yUOJ78JB0th6iBecT2Em7wf_Xdd7_1cUGH30x_gYHyN2wT7H8jyY6U431dh6ReUIILdNB6Rf2A-cCuH8</recordid><startdate>20120401</startdate><enddate>20120401</enddate><creator>Berger, Jeffrey T., MD</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7X8</scope></search><sort><creationdate>20120401</creationdate><title>Preemptive Use of Palliative Sedation and Amyotrophic Lateral Sclerosis</title><author>Berger, Jeffrey T., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c545t-224eb303ddb08497d48726862c10609d442da94f760c8468daa6e81a3bc3024e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Amyotrophic lateral sclerosis</topic><topic>Amyotrophic Lateral Sclerosis - complications</topic><topic>Amyotrophic Lateral Sclerosis - therapy</topic><topic>Anesthesia & Perioperative Care</topic><topic>Artificial respiration</topic><topic>Biological and medical sciences</topic><topic>Cerebrospinal fluid. Meninges. Spinal cord</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>Dyspnea - etiology</topic><topic>Dyspnea - prevention & control</topic><topic>Ethics</topic><topic>Extremes</topic><topic>Humans</topic><topic>Hypnotics and Sedatives - therapeutic use</topic><topic>Lorazepam - therapeutic use</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Pain Medicine</topic><topic>Palliative care</topic><topic>Palliative Care - methods</topic><topic>palliative sedation</topic><topic>Pharmacology. Drug treatments</topic><topic>Sedation</topic><topic>Symptoms</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Berger, Jeffrey T., MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pain and symptom management</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Berger, Jeffrey T., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preemptive Use of Palliative Sedation and Amyotrophic Lateral Sclerosis</atitle><jtitle>Journal of pain and symptom management</jtitle><addtitle>J Pain Symptom Manage</addtitle><date>2012-04-01</date><risdate>2012</risdate><volume>43</volume><issue>4</issue><spage>802</spage><epage>805</epage><pages>802-805</pages><issn>0885-3924</issn><eissn>1873-6513</eissn><coden>JSPME2</coden><abstract>Abstract Patients in the advanced stages of amyotrophic lateral sclerosis often are faced with the dilemma of whether to use or continue to use mechanical ventilation. Patients who elect to terminate ventilatory support may be subject to significant and even extreme respiratory symptoms. Severe dyspnea and other symptoms are sometimes treated with palliative sedation, which is generally recommended as a last resort approach to refractory symptoms. However, the preemptive use of palliative sedation is sometimes appropriate. The preemptive use of palliative sedation is examined through a case-based analysis of a patient with advanced amyotrophic lateral sclerosis.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>22464355</pmid><doi>10.1016/j.jpainsymman.2011.10.012</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of pain and symptom management, 2012-04, Vol.43 (4), p.802-805 |
| issn | 0885-3924 1873-6513 |
| language | eng |
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| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - complications Amyotrophic Lateral Sclerosis - therapy Anesthesia & Perioperative Care Artificial respiration Biological and medical sciences Cerebrospinal fluid. Meninges. Spinal cord Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dyspnea - etiology Dyspnea - prevention & control Ethics Extremes Humans Hypnotics and Sedatives - therapeutic use Lorazepam - therapeutic use Male Medical sciences Nervous system (semeiology, syndromes) Neurology Pain Medicine Palliative care Palliative Care - methods palliative sedation Pharmacology. Drug treatments Sedation Symptoms Treatment Outcome |
| title | Preemptive Use of Palliative Sedation and Amyotrophic Lateral Sclerosis |
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