Flow cytometry-based algorithm to analyze the anti-fixed Toxoplasma gondii tachyzoites IgM and IgG reactivity and diagnose human acute toxoplasmosis

In the present study we evaluated the performance of a flow cytometry-based algorithm as a new serological approach to detect antibodies to T. gondii and specific IgG avidity to diagnose acute toxoplasmosis. The results showed that using FC-AFTA-IgM assay, all serum samples from patients with acute...

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Veröffentlicht in:	Journal of immunological methods 2012-04, Vol.378 (1-2), p.33-43
Hauptverfasser:	Silva-dos-Santos, Priscila Pinto, Barros, Geisa Baptista, Mineo, José Roberto, Silva, Deise Aparecida de Oliveira, Menegaz, Mauro Hygino Weinert, Serufo, José Carlos, Dietze, Reynaldo, Martins-Filho, Olindo de Assis, Lemos, Elenice Moreira
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute toxoplasmosis Algorithms antibodies Antibodies, Protozoan - blood Antibodies, Protozoan - immunology blood serum Diagnosis Flow cytometry Flow Cytometry - methods Humans immunoglobulin G Immunoglobulin G - blood Immunoglobulin G - immunology immunoglobulin M Immunoglobulin M - blood Immunoglobulin M - immunology patients Sensitivity and Specificity Serology seroprevalence tachyzoites Toxoplasma - immunology Toxoplasma gondii toxoplasmosis Toxoplasmosis - blood Toxoplasmosis - diagnosis Toxoplasmosis - immunology Toxoplasmosis - parasitology
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