Incidence, risk factors and outcome of histological transformation in follicular lymphoma

Summary Histological transformation (HT) into diffuse large B‐cell lymphoma (DLBCL) was documented in 37 of the 281 (13%; 95% CI, 9–18) follicular lymphoma (FL) patients treated at our institute from 1979 to 2007. HT occurred at a median of 2·75 years from initial FL diagnosis and HT rate was 15% at...

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Veröffentlicht in:	British journal of haematology 2012-04, Vol.157 (2), p.188-196
Hauptverfasser:	Conconi, Annarita, Ponzio, Carlotta, Lobetti-Bodoni, Chiara, Motta, Maddalena, Rancoita, Paola M.V., Stathis, Anastasios, Moccia, Alden A., Mazzucchelli, Luca, Bertoni, Francesco, Ghielmini, Michele, Cavalli, Franco, Zucca, Emanuele
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Aged Antibodies, Monoclonal, Murine-Derived - administration & dosage Antineoplastic Agents - administration & dosage Biological and medical sciences Chemotherapy Child Child, Preschool Data processing Disease-Free Survival double prime B-cell lymphoma Female follicular lymphoma Hematologic and hematopoietic diseases histological transformation Humans Incidence Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, Follicular - complications Lymphoma, Follicular - diagnosis Lymphoma, Follicular - drug therapy Lymphoma, Follicular - mortality Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - drug therapy Lymphoma, Large B-Cell, Diffuse - etiology Lymphoma, Large B-Cell, Diffuse - mortality Male Medical sciences Middle Aged prognosis Retrospective Studies Risk Factors Rituximab Survival Survival Rate Transformation
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