ApoA-I Induction as a Potential Cardioprotective Strategy: Rationale for the SUSTAIN and ASSURE Studies

Background Considerable interest has focused on the development of therapies that target the functionality of high-density lipoproteins (HDL). Upregulation of endogenous synthesis of the major protein on HDL particles, apolipoprotein A-I (apoA-I), represents a novel approach to generation of new HDL...

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Veröffentlicht in:Cardiovascular drugs and therapy 2012-04, Vol.26 (2), p.181-187
Hauptverfasser: Nicholls, Stephen J., Gordon, Allan, Johannson, Jan, Ballantyne, Christie M., Barter, Philip J., Brewer, H. Bryan, Kastelein, John J. P., Wong, Norman C., Borgman, Marilyn R. N., Nissen, Steven E.
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