Molecular targets of the natural antioxidant pterostilbene: effect on protein kinase C, caspase-3 and apoptosis in human neutrophils in vitro

Pterostilbene, a naturally occurring phenolic derivative, exhibits various pharmacological effects, e.g. anti-cancerous, antioxidant, anti-inflammatory and anti-diabetic. Based on our previous study, we assessed the cellular and molecular effects of pterostilbene on human neutrophils and in cell fre...

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Veröffentlicht in:	Neuro-endocrinology letters 2010, Vol.31 Suppl 2, p.84-90
Hauptverfasser:	Perecko, Tomas, Drabikova, Katarina, Rackova, Lucia, Ciz, Milan, Podborska, Martina, Lojek, Antonin, Harmatha, Juraj, Smidrkal, Jan, Nosal, Radomir, Jancinova, Viera
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - pharmacology Apoptosis - drug effects Caspase 3 - metabolism Cell Survival - drug effects Computer Simulation Dose-Response Relationship, Drug Humans In Vitro Techniques Male Neutrophils - cytology Neutrophils - drug effects Neutrophils - metabolism Phosphorylation - drug effects Protein Kinase C - metabolism Stilbenes - pharmacology
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