Molecular genetics external quality assessment pilot scheme for KRAS analysis in metastatic colorectal cancer

Laboratories are increasingly required to perform molecular tests for the detection of mutations in the KRAS gene in metastatic colorectal cancers to allow better clinical management and more effective treatment for these patients. KRAS mutation status predicts a patient's likely response to th...

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Veröffentlicht in:	Genetic testing and molecular biomarkers 2011-11, Vol.15 (11), p.777-783
Hauptverfasser:	Deans, Zandra C, Tull, Justyna, Beighton, Gemma, Abbs, Stephen, Robinson, David O, Butler, Rachel
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Humanized Antineoplastic Agents - therapeutic use Care and treatment Cetuximab Colorectal cancer Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Diagnosis DNA Mutational Analysis Drug Resistance, Neoplasm - genetics Evaluation Studies as Topic Female Gene mutations Genetic aspects Humans Male Molecular Biology Molecular genetics Mutation Neoplasm Metastasis Pilot Projects Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins p21(ras) Quality Assurance, Health Care ras Proteins - genetics United Kingdom
Online-Zugang:	Volltext
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