Tomatidine acts in synergy with aminoglycoside antibiotics against multiresistant Staphylococcus aureus and prevents virulence gene expression

Objectives This study characterized the multiple biological activities of the natural compound tomatidine against Staphylococcus aureus. Notably, this work examined the antibacterial activity of tomatidine in combination with other antibiotics and the influence of this compound on the expression of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of antimicrobial chemotherapy 2012-03, Vol.67 (3), p.559-568
Hauptverfasser:	Mitchell, Gabriel, Lafrance, Myriame, Boulanger, Simon, Séguin, David Lalonde, Guay, Isabelle, Gattuso, Mariza, Marsault, Éric, Bouarab, Kamal, Malouin, François
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoglycosides - pharmacology Animals Anti-Bacterial Agents - pharmacology Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Antimicrobial agents Bacterial diseases Biological and medical sciences Culture Media - chemistry Drug Resistance, Multiple, Bacterial - drug effects Drug Synergism Errors of metabolism Erythrocytes - microbiology Gene expression Gene Expression Profiling Gene Expression Regulation, Bacterial - drug effects Hemolysin Proteins - antagonists & inhibitors Hemolysis Horses Human bacterial diseases Infectious diseases Medical sciences Metabolic diseases Microbial Sensitivity Tests Microbial Viability - drug effects Miscellaneous hereditary metabolic disorders Pharmacology. Drug treatments Real-Time Polymerase Chain Reaction Staphylococcal infections, streptococcal infections, pneumococcal infections Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - pathogenicity Staphylococcus infections Time Factors Tomatine - analogs & derivatives Tomatine - pharmacology Virology Virulence Virulence Factors - antagonists & inhibitors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!