Human cytomegalovirus infection and atherothrombosis

Vascular endothelium, as a key regulator of hemostasis, mediates vascular dilatation, prevents platelet adhesion, and inhibits thrombin generation. Endothelial dysfunction caused by acute or chronic inflammation, such as in atherosclerosis, creates a proinflammatory environment which supports leukoc...

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Veröffentlicht in:	Journal of thrombosis and thrombolysis 2012-02, Vol.33 (2), p.160-172
Hauptverfasser:	Popović, Milan, Smiljanić, Katarina, Dobutović, Branislava, Syrovets, Tatiana, Simmet, Thomas, Isenović, Esma R.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Apoptosis Arteriosclerosis Atherosclerosis - immunology Atherosclerosis - pathology Blood Cardiology Cell activation Cell migration Coagulation Coagulation factor Xa Cytomegalovirus - immunology Cytomegalovirus Infections - immunology Cytomegalovirus Infections - pathology Endothelial cells Endothelium Endothelium, Vascular - immunology Endothelium, Vascular - pathology fibrin Hematology hemostasis Human cytomegalovirus Humans Inflammation Leukocyte migration Lipids Macrophages Medicine Medicine & Public Health Monocytes Persistent infection Plaques Platelet-derived growth factor receptors Platelets Proteolysis restenosis Reviews Signal transduction Smooth muscle Thrombin thrombolysis Thrombosis Thrombosis - immunology Thrombosis - pathology Wounds
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