X Chromosome Inactivation and Autoimmunity

Autoimmune diseases appear to have multiple contributing factors including genetics, epigenetics, environmental factors, and aging. The predominance of females among patients with autoimmune diseases suggests possible involvement of the X chromosome and X chromosome inactivation. X chromosome inacti...

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Veröffentlicht in:	Clinical reviews in allergy & immunology 2010-08, Vol.39 (1), p.20-29
1. Verfasser:	Brooks, Wesley H
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Allergology Animals Autoimmune diseases Autoimmune Diseases - genetics Autoimmune Diseases - immunology Autoimmune Diseases - metabolism Autoimmunity Chromosomes Chromosomes, Human, X - immunology Disease Susceptibility DNA Methylation Environmental factors epigenetics Female Gene Silencing - immunology Genes Granulomatous Disease, Chronic - genetics Humans Hydrolases - immunology Hydrolases - metabolism Immunology Internal Medicine Medicine Medicine & Public Health polyamines Reviews Sex Chromosome Disorders - genetics Sex Chromosome Disorders - immunology Sex Chromosome Disorders - metabolism Sex Factors Signal Transduction - immunology Spermine - immunology X chromosome X Chromosome Inactivation X inactivation
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