Neurological manifestations of coinfection with HIV and human T-lymphotropic virus type 1
HIV-individuals are at risk for human T-lymphotropic virus (HTLV) coinfection and neurological diseases. Little is known about the impact of HAART among coinfected patients. In this study, 47 out of 428 HIV individuals were coinfected with HTLV (10.9%). Coinfection was an independent variable associ...
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| Veröffentlicht in: | AIDS (London) 2012-02, Vol.26 (4), p.521-523 |
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| creator | SILVA, Marcus T. T NEVES, Elizabeth S GRINSZTEJN, Beatriz MELO ESPINDOLA, Otavio De SCHOR, Doris ARAUJO, Abelardo |
| description | HIV-individuals are at risk for human T-lymphotropic virus (HTLV) coinfection and neurological diseases. Little is known about the impact of HAART among coinfected patients. In this study, 47 out of 428 HIV individuals were coinfected with HTLV (10.9%). Coinfection was an independent variable associated with neurological outcome (odds ratio 8.73). Coinfection was associated with myelopathy [chi square (X(2)) = 93, P < 0.001], peripheral neuropathy (X(2) = 6.5, P = 0.01), and hepatitis C virus infection (X(2) = 36.5, P < 0.001). HAART did not appear to protect against neurological diseases and had no impact on HTLV proviral load. |
| doi_str_mv | 10.1097/QAD.0b013e32834c4a3e |
| format | Article |
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HAART did not appear to protect against neurological diseases and had no impact on HTLV proviral load.</description><subject>AIDS/HIV</subject><subject>Antiretroviral Therapy, Highly Active</subject><subject>Biological and medical sciences</subject><subject>CD4 Lymphocyte Count</subject><subject>Coinfection</subject><subject>Deltaretrovirus Antibodies - blood</subject><subject>Female</subject><subject>Hepatitis C Antibodies - blood</subject><subject>Hepatitis C virus</subject><subject>HIV Infections - complications</subject><subject>HIV Infections - physiopathology</subject><subject>HTLV-II Infections - complications</subject><subject>HTLV-II Infections - physiopathology</subject><subject>Human immunodeficiency virus</subject><subject>Human T-lymphotropic virus</subject><subject>Human T-lymphotropic virus 1 - pathogenicity</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Odds Ratio</subject><subject>Peripheral Nervous System Diseases - physiopathology</subject><subject>Peripheral Nervous System Diseases - virology</subject><subject>Spinal Cord Diseases - virology</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. 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| fulltext | fulltext |
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| ispartof | AIDS (London), 2012-02, Vol.26 (4), p.521-523 |
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| source | MEDLINE; Journals@Ovid Complete; EZB-FREE-00999 freely available EZB journals |
| subjects | AIDS/HIV Antiretroviral Therapy, Highly Active Biological and medical sciences CD4 Lymphocyte Count Coinfection Deltaretrovirus Antibodies - blood Female Hepatitis C Antibodies - blood Hepatitis C virus HIV Infections - complications HIV Infections - physiopathology HTLV-II Infections - complications HTLV-II Infections - physiopathology Human immunodeficiency virus Human T-lymphotropic virus Human T-lymphotropic virus 1 - pathogenicity Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Male Medical sciences Middle Aged Odds Ratio Peripheral Nervous System Diseases - physiopathology Peripheral Nervous System Diseases - virology Spinal Cord Diseases - virology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load |
| title | Neurological manifestations of coinfection with HIV and human T-lymphotropic virus type 1 |
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