Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies
Results of studies on fish consumption and CHD mortality are inconsistent. The present updated meta-analysis was conducted to investigate the up-to-date pooling effects. A random-effects model was used to pool the risk estimates. Generalized least-squares regression and restricted cubic splines were...
Gespeichert in:
| Veröffentlicht in: | Public health nutrition 2012-04, Vol.15 (4), p.725-737 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 737 |
|---|---|
| container_issue | 4 |
| container_start_page | 725 |
| container_title | Public health nutrition |
| container_volume | 15 |
| creator | Zheng, Jusheng Huang, Tao Yu, Yinghua Hu, Xiaojie Yang, Bin Li, Duo |
| description | Results of studies on fish consumption and CHD mortality are inconsistent. The present updated meta-analysis was conducted to investigate the up-to-date pooling effects.
A random-effects model was used to pool the risk estimates. Generalized least-squares regression and restricted cubic splines were used to assess the possible dose-response relationship. Subgroup analyses were conducted to examine the sources of heterogeneity.
PubMed and ISI Web of Science databases up to September 2010 were searched and secondary referencing qualified for inclusion in the study.
Seventeen cohorts with 315,812 participants and average follow-up period of 15·9 years were identified.
Compared with the lowest fish intake (5 servings/week). The dose-response analysis indicated that every 15 g/d increment of fish intake decreased the risk of CHD mortality by 6% (RR = 0·94; 95% CI 0·90, 0·98). The method of dietary assessment, gender and energy adjustment affected the results remarkably.
Our results indicate that either low (1 serving/week) or moderate fish consumption (2-4 servings/week) has a significantly beneficial effect on the prevention of CHD mortality. High fish consumption (>5 servings/week) possesses only a marginally protective effect on CHD mortality, possibly due to the limited studies included in this group. |
| doi_str_mv | 10.1017/S1368980011002254 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_954640695</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1017_S1368980011002254</cupid><sourcerecordid>926153425</sourcerecordid><originalsourceid>FETCH-LOGICAL-c512t-8b3770e903d7193a77489e8c3eae13e3d55cb2c007567290917241fb7207555b3</originalsourceid><addsrcrecordid>eNqFkU9LxDAQxYMo7rr6AbxI8OKpmkmapvEmq6vCggcVvJW0nbpd-s8mFfbbm2VXBUU8zTDze29IHiHHwM6Bgbp4BBHFOmYMgDHOZbhDxhAqGXDF1a7v_TpY70fkwNolY0wqpfbJiIOGkMt4TF5mpV3QrG3sUHeubBtqmpxO765p3fbOVKVbXfoRHbrcOMxpjc4EpjHVypaWtgW1-I6NQ2y8ycJLqHVDXqI9JHuFqSwebeuEPM9unqZ3wfzh9n56NQ8yCdwFcSqUYqiZyBVoYZQKY41xJtAgCBS5lFnKM8aUjBTXTIPiIRSp4n4iZSom5Gzj2_Xt24DWJXVpM6wq02A72ETLMApZpOX_JI9ACv8tnjz9QS7bofePXkMy4lLGsYdgA2V9a22PRdL1ZW36VQIsWceT_IrHa062xkNaY_6l-MzDA2Jrauq0L_NX_D79t-0HYb2XVg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>925625588</pqid></control><display><type>article</type><title>Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Zheng, Jusheng ; Huang, Tao ; Yu, Yinghua ; Hu, Xiaojie ; Yang, Bin ; Li, Duo</creator><creatorcontrib>Zheng, Jusheng ; Huang, Tao ; Yu, Yinghua ; Hu, Xiaojie ; Yang, Bin ; Li, Duo</creatorcontrib><description>Results of studies on fish consumption and CHD mortality are inconsistent. The present updated meta-analysis was conducted to investigate the up-to-date pooling effects.
A random-effects model was used to pool the risk estimates. Generalized least-squares regression and restricted cubic splines were used to assess the possible dose-response relationship. Subgroup analyses were conducted to examine the sources of heterogeneity.
PubMed and ISI Web of Science databases up to September 2010 were searched and secondary referencing qualified for inclusion in the study.
Seventeen cohorts with 315,812 participants and average follow-up period of 15·9 years were identified.
Compared with the lowest fish intake (<1 serving/month or 1-3 servings/month), the pooled relative risk (RR) of fish intake on CHD mortality was 0·84 (95% CI 0·75, 0·95) for low fish intake (1 serving/week), 0·79 (95% CI 0·67, 0·92) for moderate fish intake (2-4 servings/week) and 0·83 (95% CI 0·68, 1·01) for high fish intake (>5 servings/week). The dose-response analysis indicated that every 15 g/d increment of fish intake decreased the risk of CHD mortality by 6% (RR = 0·94; 95% CI 0·90, 0·98). The method of dietary assessment, gender and energy adjustment affected the results remarkably.
Our results indicate that either low (1 serving/week) or moderate fish consumption (2-4 servings/week) has a significantly beneficial effect on the prevention of CHD mortality. High fish consumption (>5 servings/week) possesses only a marginally protective effect on CHD mortality, possibly due to the limited studies included in this group.</description><identifier>ISSN: 1368-9800</identifier><identifier>EISSN: 1475-2727</identifier><identifier>DOI: 10.1017/S1368980011002254</identifier><identifier>PMID: 21914258</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Animals ; Cardiovascular disease ; Cardiovascular Diseases - mortality ; Cardiovascular Diseases - prevention & control ; Cohort analysis ; Cohort Studies ; Diet - statistics & numerical data ; Diets ; Drug dosages ; Fatty acids ; Fish ; Fish oils ; Fishes ; Heart attacks ; Heterogeneity ; Humans ; Meta-analysis ; Mortality ; Nutrition and health ; Risk Assessment ; Risk reduction ; Risk Reduction Behavior ; Seafood</subject><ispartof>Public health nutrition, 2012-04, Vol.15 (4), p.725-737</ispartof><rights>Copyright © The Authors 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c512t-8b3770e903d7193a77489e8c3eae13e3d55cb2c007567290917241fb7207555b3</citedby><cites>FETCH-LOGICAL-c512t-8b3770e903d7193a77489e8c3eae13e3d55cb2c007567290917241fb7207555b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21914258$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zheng, Jusheng</creatorcontrib><creatorcontrib>Huang, Tao</creatorcontrib><creatorcontrib>Yu, Yinghua</creatorcontrib><creatorcontrib>Hu, Xiaojie</creatorcontrib><creatorcontrib>Yang, Bin</creatorcontrib><creatorcontrib>Li, Duo</creatorcontrib><title>Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies</title><title>Public health nutrition</title><addtitle>Public Health Nutr</addtitle><description>Results of studies on fish consumption and CHD mortality are inconsistent. The present updated meta-analysis was conducted to investigate the up-to-date pooling effects.
A random-effects model was used to pool the risk estimates. Generalized least-squares regression and restricted cubic splines were used to assess the possible dose-response relationship. Subgroup analyses were conducted to examine the sources of heterogeneity.
PubMed and ISI Web of Science databases up to September 2010 were searched and secondary referencing qualified for inclusion in the study.
Seventeen cohorts with 315,812 participants and average follow-up period of 15·9 years were identified.
Compared with the lowest fish intake (<1 serving/month or 1-3 servings/month), the pooled relative risk (RR) of fish intake on CHD mortality was 0·84 (95% CI 0·75, 0·95) for low fish intake (1 serving/week), 0·79 (95% CI 0·67, 0·92) for moderate fish intake (2-4 servings/week) and 0·83 (95% CI 0·68, 1·01) for high fish intake (>5 servings/week). The dose-response analysis indicated that every 15 g/d increment of fish intake decreased the risk of CHD mortality by 6% (RR = 0·94; 95% CI 0·90, 0·98). The method of dietary assessment, gender and energy adjustment affected the results remarkably.
Our results indicate that either low (1 serving/week) or moderate fish consumption (2-4 servings/week) has a significantly beneficial effect on the prevention of CHD mortality. High fish consumption (>5 servings/week) possesses only a marginally protective effect on CHD mortality, possibly due to the limited studies included in this group.</description><subject>Animals</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular Diseases - mortality</subject><subject>Cardiovascular Diseases - prevention & control</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Diet - statistics & numerical data</subject><subject>Diets</subject><subject>Drug dosages</subject><subject>Fatty acids</subject><subject>Fish</subject><subject>Fish oils</subject><subject>Fishes</subject><subject>Heart attacks</subject><subject>Heterogeneity</subject><subject>Humans</subject><subject>Meta-analysis</subject><subject>Mortality</subject><subject>Nutrition and health</subject><subject>Risk Assessment</subject><subject>Risk reduction</subject><subject>Risk Reduction Behavior</subject><subject>Seafood</subject><issn>1368-9800</issn><issn>1475-2727</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNqFkU9LxDAQxYMo7rr6AbxI8OKpmkmapvEmq6vCggcVvJW0nbpd-s8mFfbbm2VXBUU8zTDze29IHiHHwM6Bgbp4BBHFOmYMgDHOZbhDxhAqGXDF1a7v_TpY70fkwNolY0wqpfbJiIOGkMt4TF5mpV3QrG3sUHeubBtqmpxO765p3fbOVKVbXfoRHbrcOMxpjc4EpjHVypaWtgW1-I6NQ2y8ycJLqHVDXqI9JHuFqSwebeuEPM9unqZ3wfzh9n56NQ8yCdwFcSqUYqiZyBVoYZQKY41xJtAgCBS5lFnKM8aUjBTXTIPiIRSp4n4iZSom5Gzj2_Xt24DWJXVpM6wq02A72ETLMApZpOX_JI9ACv8tnjz9QS7bofePXkMy4lLGsYdgA2V9a22PRdL1ZW36VQIsWceT_IrHa062xkNaY_6l-MzDA2Jrauq0L_NX_D79t-0HYb2XVg</recordid><startdate>20120401</startdate><enddate>20120401</enddate><creator>Zheng, Jusheng</creator><creator>Huang, Tao</creator><creator>Yu, Yinghua</creator><creator>Hu, Xiaojie</creator><creator>Yang, Bin</creator><creator>Li, Duo</creator><general>Cambridge University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RQ</scope><scope>7RV</scope><scope>7T2</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>7U1</scope><scope>7U2</scope></search><sort><creationdate>20120401</creationdate><title>Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies</title><author>Zheng, Jusheng ; Huang, Tao ; Yu, Yinghua ; Hu, Xiaojie ; Yang, Bin ; Li, Duo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c512t-8b3770e903d7193a77489e8c3eae13e3d55cb2c007567290917241fb7207555b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animals</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular Diseases - mortality</topic><topic>Cardiovascular Diseases - prevention & control</topic><topic>Cohort analysis</topic><topic>Cohort Studies</topic><topic>Diet - statistics & numerical data</topic><topic>Diets</topic><topic>Drug dosages</topic><topic>Fatty acids</topic><topic>Fish</topic><topic>Fish oils</topic><topic>Fishes</topic><topic>Heart attacks</topic><topic>Heterogeneity</topic><topic>Humans</topic><topic>Meta-analysis</topic><topic>Mortality</topic><topic>Nutrition and health</topic><topic>Risk Assessment</topic><topic>Risk reduction</topic><topic>Risk Reduction Behavior</topic><topic>Seafood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zheng, Jusheng</creatorcontrib><creatorcontrib>Huang, Tao</creatorcontrib><creatorcontrib>Yu, Yinghua</creatorcontrib><creatorcontrib>Hu, Xiaojie</creatorcontrib><creatorcontrib>Yang, Bin</creatorcontrib><creatorcontrib>Li, Duo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Career & Technical Education Database</collection><collection>Nursing & Allied Health Database</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><jtitle>Public health nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zheng, Jusheng</au><au>Huang, Tao</au><au>Yu, Yinghua</au><au>Hu, Xiaojie</au><au>Yang, Bin</au><au>Li, Duo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies</atitle><jtitle>Public health nutrition</jtitle><addtitle>Public Health Nutr</addtitle><date>2012-04-01</date><risdate>2012</risdate><volume>15</volume><issue>4</issue><spage>725</spage><epage>737</epage><pages>725-737</pages><issn>1368-9800</issn><eissn>1475-2727</eissn><abstract>Results of studies on fish consumption and CHD mortality are inconsistent. The present updated meta-analysis was conducted to investigate the up-to-date pooling effects.
A random-effects model was used to pool the risk estimates. Generalized least-squares regression and restricted cubic splines were used to assess the possible dose-response relationship. Subgroup analyses were conducted to examine the sources of heterogeneity.
PubMed and ISI Web of Science databases up to September 2010 were searched and secondary referencing qualified for inclusion in the study.
Seventeen cohorts with 315,812 participants and average follow-up period of 15·9 years were identified.
Compared with the lowest fish intake (<1 serving/month or 1-3 servings/month), the pooled relative risk (RR) of fish intake on CHD mortality was 0·84 (95% CI 0·75, 0·95) for low fish intake (1 serving/week), 0·79 (95% CI 0·67, 0·92) for moderate fish intake (2-4 servings/week) and 0·83 (95% CI 0·68, 1·01) for high fish intake (>5 servings/week). The dose-response analysis indicated that every 15 g/d increment of fish intake decreased the risk of CHD mortality by 6% (RR = 0·94; 95% CI 0·90, 0·98). The method of dietary assessment, gender and energy adjustment affected the results remarkably.
Our results indicate that either low (1 serving/week) or moderate fish consumption (2-4 servings/week) has a significantly beneficial effect on the prevention of CHD mortality. High fish consumption (>5 servings/week) possesses only a marginally protective effect on CHD mortality, possibly due to the limited studies included in this group.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>21914258</pmid><doi>10.1017/S1368980011002254</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1368-9800 |
| ispartof | Public health nutrition, 2012-04, Vol.15 (4), p.725-737 |
| issn | 1368-9800 1475-2727 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_954640695 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Animals Cardiovascular disease Cardiovascular Diseases - mortality Cardiovascular Diseases - prevention & control Cohort analysis Cohort Studies Diet - statistics & numerical data Diets Drug dosages Fatty acids Fish Fish oils Fishes Heart attacks Heterogeneity Humans Meta-analysis Mortality Nutrition and health Risk Assessment Risk reduction Risk Reduction Behavior Seafood |
| title | Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T02%3A05%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Fish%20consumption%20and%20CHD%20mortality:%20an%20updated%20meta-analysis%20of%20seventeen%20cohort%20studies&rft.jtitle=Public%20health%20nutrition&rft.au=Zheng,%20Jusheng&rft.date=2012-04-01&rft.volume=15&rft.issue=4&rft.spage=725&rft.epage=737&rft.pages=725-737&rft.issn=1368-9800&rft.eissn=1475-2727&rft_id=info:doi/10.1017/S1368980011002254&rft_dat=%3Cproquest_cross%3E926153425%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=925625588&rft_id=info:pmid/21914258&rft_cupid=10_1017_S1368980011002254&rfr_iscdi=true |