Effect of swimming on lipid metabolism, LDL oxidation resistance, and atherogenesis in apolipoprotein E knock-out mice
Fonseca TR, Botelho FV, De Lima DC, Ferraz FO, Dos Santos LAVDR, Mendes TT, Lima NRV, Alvarez-Leite JI. Effect of Swimming on Lipid Metabolism, LDL Oxidation Resistance, and Atherogenesis in Apolipoprotein E Knock-Out Mice. JEPonline 2011; 14(4):49-58. This study evaluated the effects of 6 weeks of...
Gespeichert in:
Veröffentlicht in: | Journal of exercise physiology online 2011-08, Vol.14 (4), p.49-58 |
---|---|
Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 58 |
---|---|
container_issue | 4 |
container_start_page | 49 |
container_title | Journal of exercise physiology online |
container_volume | 14 |
creator | Fonseca, Tatiana R Botelho, Frangoise V De Lima, Daniel C Ferraz, Fernanda O Dos Santos, Lucas A.V.D.R Mendes, Thiago T Lima, Nilo R.V Alvarez-Leite, Jacqueline I |
description | Fonseca TR, Botelho FV, De Lima DC, Ferraz FO, Dos Santos LAVDR, Mendes TT, Lima NRV, Alvarez-Leite JI. Effect of Swimming on Lipid Metabolism, LDL Oxidation Resistance, and Atherogenesis in Apolipoprotein E Knock-Out Mice. JEPonline 2011; 14(4):49-58. This study evaluated the effects of 6 weeks of swimming on lipid metabolism, oxidation resistance, and atherosclerosis in 6-week-old female apolipoprotein E-deficient mice (apo[E.sup.-/-]). The mice were divided into a control group (n=7) and a treatment group (n=7). Mice in the treatment group were required to swim 10 min x [d.sup.-1], 5 d x wk-1 for 6 weeks (which was increased by 10 min x [d.sup.-1] until the mice swam continuously for 1 hr). Plasma total cholesterol was evaluated before and after the experiment. Liver and fecal lipids, lipid oxidation resistance, and atherosclerotic area of thoracic and abdominal aorta were evaluated after euthanasia. Body weight, lipid metabolism, and lipid oxidation resistance were similar in both groups. Relative index was statistically decreased in the experimental group, thus suggesting that the apo[E.sup.-/-] mice that underwent the swimming exercise exhibited decreased atherosclerotic lesions in the aorta. However, the decrease was not due to changes in lipid metabolism or lipid oxidation resistance profile. Key Words: Physical Exercise, Atherosclerosis, Lipid Metabolism |
format | Article |
fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_954639105</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A361184750</galeid><sourcerecordid>A361184750</sourcerecordid><originalsourceid>FETCH-LOGICAL-g200t-ca26f91189248edef3748da8d55b2194aac92b57bb06e862f0e058da6c123c503</originalsourceid><addsrcrecordid>eNptkN9LwzAQx4soOKf_Q0DQl1XStGmbxzE3FQq-6HNJ00sXlya1SdU_38z5MEHu4X59vsfdnUSzBLMiZgVNTo_i8-jCuTeMCc7KYhZ9rKUE4ZGVyH2qvlemQ9YgrQbVoh48b6xWrl-g6r5C9ku13KvQH8Ep57kRsEDctIj7LYy2A7OvI2UQH4JusMNoPYR0jXbGil1sJ496JeAyOpNcO7j69fPodbN-WT3G1fPD02pZxR3B2MeCk1yyJCkZyUpoQaZFVra8bCltSMIyzgUjDS2aBudQ5kRiwDQAuUhIKihO59HtYW5Y5H0C5-teOQFacwN2cjWjWZ6yBNNAXh_IjmuolZHWj1zs6XqZ5mGFrPiZd_cPFayFcJY1IFWo_xHcHAm2wLXfOqun_RfdMfgN_lGD5A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>954639105</pqid></control><display><type>article</type><title>Effect of swimming on lipid metabolism, LDL oxidation resistance, and atherogenesis in apolipoprotein E knock-out mice</title><source>EZB-FREE-00999 freely available EZB journals</source><creator>Fonseca, Tatiana R ; Botelho, Frangoise V ; De Lima, Daniel C ; Ferraz, Fernanda O ; Dos Santos, Lucas A.V.D.R ; Mendes, Thiago T ; Lima, Nilo R.V ; Alvarez-Leite, Jacqueline I</creator><creatorcontrib>Fonseca, Tatiana R ; Botelho, Frangoise V ; De Lima, Daniel C ; Ferraz, Fernanda O ; Dos Santos, Lucas A.V.D.R ; Mendes, Thiago T ; Lima, Nilo R.V ; Alvarez-Leite, Jacqueline I</creatorcontrib><description>Fonseca TR, Botelho FV, De Lima DC, Ferraz FO, Dos Santos LAVDR, Mendes TT, Lima NRV, Alvarez-Leite JI. Effect of Swimming on Lipid Metabolism, LDL Oxidation Resistance, and Atherogenesis in Apolipoprotein E Knock-Out Mice. JEPonline 2011; 14(4):49-58. This study evaluated the effects of 6 weeks of swimming on lipid metabolism, oxidation resistance, and atherosclerosis in 6-week-old female apolipoprotein E-deficient mice (apo[E.sup.-/-]). The mice were divided into a control group (n=7) and a treatment group (n=7). Mice in the treatment group were required to swim 10 min x [d.sup.-1], 5 d x wk-1 for 6 weeks (which was increased by 10 min x [d.sup.-1] until the mice swam continuously for 1 hr). Plasma total cholesterol was evaluated before and after the experiment. Liver and fecal lipids, lipid oxidation resistance, and atherosclerotic area of thoracic and abdominal aorta were evaluated after euthanasia. Body weight, lipid metabolism, and lipid oxidation resistance were similar in both groups. Relative index was statistically decreased in the experimental group, thus suggesting that the apo[E.sup.-/-] mice that underwent the swimming exercise exhibited decreased atherosclerotic lesions in the aorta. However, the decrease was not due to changes in lipid metabolism or lipid oxidation resistance profile. Key Words: Physical Exercise, Atherosclerosis, Lipid Metabolism</description><identifier>ISSN: 1097-9751</identifier><identifier>EISSN: 1097-9751</identifier><language>eng</language><publisher>American Society of Exercise Physiologists</publisher><subject>Atherosclerosis ; Care and treatment ; Exercise ; Lipid metabolism ; Low density lipoproteins ; Physiological aspects ; Physiological research ; Prevention ; Swimming</subject><ispartof>Journal of exercise physiology online, 2011-08, Vol.14 (4), p.49-58</ispartof><rights>COPYRIGHT 2011 American Society of Exercise Physiologists</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Fonseca, Tatiana R</creatorcontrib><creatorcontrib>Botelho, Frangoise V</creatorcontrib><creatorcontrib>De Lima, Daniel C</creatorcontrib><creatorcontrib>Ferraz, Fernanda O</creatorcontrib><creatorcontrib>Dos Santos, Lucas A.V.D.R</creatorcontrib><creatorcontrib>Mendes, Thiago T</creatorcontrib><creatorcontrib>Lima, Nilo R.V</creatorcontrib><creatorcontrib>Alvarez-Leite, Jacqueline I</creatorcontrib><title>Effect of swimming on lipid metabolism, LDL oxidation resistance, and atherogenesis in apolipoprotein E knock-out mice</title><title>Journal of exercise physiology online</title><description>Fonseca TR, Botelho FV, De Lima DC, Ferraz FO, Dos Santos LAVDR, Mendes TT, Lima NRV, Alvarez-Leite JI. Effect of Swimming on Lipid Metabolism, LDL Oxidation Resistance, and Atherogenesis in Apolipoprotein E Knock-Out Mice. JEPonline 2011; 14(4):49-58. This study evaluated the effects of 6 weeks of swimming on lipid metabolism, oxidation resistance, and atherosclerosis in 6-week-old female apolipoprotein E-deficient mice (apo[E.sup.-/-]). The mice were divided into a control group (n=7) and a treatment group (n=7). Mice in the treatment group were required to swim 10 min x [d.sup.-1], 5 d x wk-1 for 6 weeks (which was increased by 10 min x [d.sup.-1] until the mice swam continuously for 1 hr). Plasma total cholesterol was evaluated before and after the experiment. Liver and fecal lipids, lipid oxidation resistance, and atherosclerotic area of thoracic and abdominal aorta were evaluated after euthanasia. Body weight, lipid metabolism, and lipid oxidation resistance were similar in both groups. Relative index was statistically decreased in the experimental group, thus suggesting that the apo[E.sup.-/-] mice that underwent the swimming exercise exhibited decreased atherosclerotic lesions in the aorta. However, the decrease was not due to changes in lipid metabolism or lipid oxidation resistance profile. Key Words: Physical Exercise, Atherosclerosis, Lipid Metabolism</description><subject>Atherosclerosis</subject><subject>Care and treatment</subject><subject>Exercise</subject><subject>Lipid metabolism</subject><subject>Low density lipoproteins</subject><subject>Physiological aspects</subject><subject>Physiological research</subject><subject>Prevention</subject><subject>Swimming</subject><issn>1097-9751</issn><issn>1097-9751</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNptkN9LwzAQx4soOKf_Q0DQl1XStGmbxzE3FQq-6HNJ00sXlya1SdU_38z5MEHu4X59vsfdnUSzBLMiZgVNTo_i8-jCuTeMCc7KYhZ9rKUE4ZGVyH2qvlemQ9YgrQbVoh48b6xWrl-g6r5C9ku13KvQH8Ep57kRsEDctIj7LYy2A7OvI2UQH4JusMNoPYR0jXbGil1sJ496JeAyOpNcO7j69fPodbN-WT3G1fPD02pZxR3B2MeCk1yyJCkZyUpoQaZFVra8bCltSMIyzgUjDS2aBudQ5kRiwDQAuUhIKihO59HtYW5Y5H0C5-teOQFacwN2cjWjWZ6yBNNAXh_IjmuolZHWj1zs6XqZ5mGFrPiZd_cPFayFcJY1IFWo_xHcHAm2wLXfOqun_RfdMfgN_lGD5A</recordid><startdate>20110801</startdate><enddate>20110801</enddate><creator>Fonseca, Tatiana R</creator><creator>Botelho, Frangoise V</creator><creator>De Lima, Daniel C</creator><creator>Ferraz, Fernanda O</creator><creator>Dos Santos, Lucas A.V.D.R</creator><creator>Mendes, Thiago T</creator><creator>Lima, Nilo R.V</creator><creator>Alvarez-Leite, Jacqueline I</creator><general>American Society of Exercise Physiologists</general><scope>7TS</scope></search><sort><creationdate>20110801</creationdate><title>Effect of swimming on lipid metabolism, LDL oxidation resistance, and atherogenesis in apolipoprotein E knock-out mice</title><author>Fonseca, Tatiana R ; Botelho, Frangoise V ; De Lima, Daniel C ; Ferraz, Fernanda O ; Dos Santos, Lucas A.V.D.R ; Mendes, Thiago T ; Lima, Nilo R.V ; Alvarez-Leite, Jacqueline I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g200t-ca26f91189248edef3748da8d55b2194aac92b57bb06e862f0e058da6c123c503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Atherosclerosis</topic><topic>Care and treatment</topic><topic>Exercise</topic><topic>Lipid metabolism</topic><topic>Low density lipoproteins</topic><topic>Physiological aspects</topic><topic>Physiological research</topic><topic>Prevention</topic><topic>Swimming</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fonseca, Tatiana R</creatorcontrib><creatorcontrib>Botelho, Frangoise V</creatorcontrib><creatorcontrib>De Lima, Daniel C</creatorcontrib><creatorcontrib>Ferraz, Fernanda O</creatorcontrib><creatorcontrib>Dos Santos, Lucas A.V.D.R</creatorcontrib><creatorcontrib>Mendes, Thiago T</creatorcontrib><creatorcontrib>Lima, Nilo R.V</creatorcontrib><creatorcontrib>Alvarez-Leite, Jacqueline I</creatorcontrib><collection>Physical Education Index</collection><jtitle>Journal of exercise physiology online</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fonseca, Tatiana R</au><au>Botelho, Frangoise V</au><au>De Lima, Daniel C</au><au>Ferraz, Fernanda O</au><au>Dos Santos, Lucas A.V.D.R</au><au>Mendes, Thiago T</au><au>Lima, Nilo R.V</au><au>Alvarez-Leite, Jacqueline I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of swimming on lipid metabolism, LDL oxidation resistance, and atherogenesis in apolipoprotein E knock-out mice</atitle><jtitle>Journal of exercise physiology online</jtitle><date>2011-08-01</date><risdate>2011</risdate><volume>14</volume><issue>4</issue><spage>49</spage><epage>58</epage><pages>49-58</pages><issn>1097-9751</issn><eissn>1097-9751</eissn><abstract>Fonseca TR, Botelho FV, De Lima DC, Ferraz FO, Dos Santos LAVDR, Mendes TT, Lima NRV, Alvarez-Leite JI. Effect of Swimming on Lipid Metabolism, LDL Oxidation Resistance, and Atherogenesis in Apolipoprotein E Knock-Out Mice. JEPonline 2011; 14(4):49-58. This study evaluated the effects of 6 weeks of swimming on lipid metabolism, oxidation resistance, and atherosclerosis in 6-week-old female apolipoprotein E-deficient mice (apo[E.sup.-/-]). The mice were divided into a control group (n=7) and a treatment group (n=7). Mice in the treatment group were required to swim 10 min x [d.sup.-1], 5 d x wk-1 for 6 weeks (which was increased by 10 min x [d.sup.-1] until the mice swam continuously for 1 hr). Plasma total cholesterol was evaluated before and after the experiment. Liver and fecal lipids, lipid oxidation resistance, and atherosclerotic area of thoracic and abdominal aorta were evaluated after euthanasia. Body weight, lipid metabolism, and lipid oxidation resistance were similar in both groups. Relative index was statistically decreased in the experimental group, thus suggesting that the apo[E.sup.-/-] mice that underwent the swimming exercise exhibited decreased atherosclerotic lesions in the aorta. However, the decrease was not due to changes in lipid metabolism or lipid oxidation resistance profile. Key Words: Physical Exercise, Atherosclerosis, Lipid Metabolism</abstract><pub>American Society of Exercise Physiologists</pub><tpages>10</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1097-9751 |
ispartof | Journal of exercise physiology online, 2011-08, Vol.14 (4), p.49-58 |
issn | 1097-9751 1097-9751 |
language | eng |
recordid | cdi_proquest_miscellaneous_954639105 |
source | EZB-FREE-00999 freely available EZB journals |
subjects | Atherosclerosis Care and treatment Exercise Lipid metabolism Low density lipoproteins Physiological aspects Physiological research Prevention Swimming |
title | Effect of swimming on lipid metabolism, LDL oxidation resistance, and atherogenesis in apolipoprotein E knock-out mice |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T13%3A35%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20swimming%20on%20lipid%20metabolism,%20LDL%20oxidation%20resistance,%20and%20atherogenesis%20in%20apolipoprotein%20E%20knock-out%20mice&rft.jtitle=Journal%20of%20exercise%20physiology%20online&rft.au=Fonseca,%20Tatiana%20R&rft.date=2011-08-01&rft.volume=14&rft.issue=4&rft.spage=49&rft.epage=58&rft.pages=49-58&rft.issn=1097-9751&rft.eissn=1097-9751&rft_id=info:doi/&rft_dat=%3Cgale_proqu%3EA361184750%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=954639105&rft_id=info:pmid/&rft_galeid=A361184750&rfr_iscdi=true |