Anal cancer with cerebral metastasis: a case report
Carcinoma of the anal canal is a relatively rare cancer with a low propensity for metastasis. A literature review identifies two cases of brain metastases from anal cancer. The authors present the case of a 63-year-old female with poorly differentiated squamous cell carcinoma of the anal canal who p...
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| Veröffentlicht in: | Journal of neuro-oncology 2011, Vol.101 (1), p.141-143 |
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| container_title | Journal of neuro-oncology |
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| creator | Rughani, Anand I. Lin, Chih Tranmer, Bruce I. Wilson, James T. |
| description | Carcinoma of the anal canal is a relatively rare cancer with a low propensity for metastasis. A literature review identifies two cases of brain metastases from anal cancer. The authors present the case of a 63-year-old female with poorly differentiated squamous cell carcinoma of the anal canal who presented with a solitary dural-based enhancing lesion of the right parietal area. The patient underwent craniectomy and tumor resection. Histopathology confirmed the cerebral lesion to be a poorly differentiated squamous cell carcinoma, consistent with the known primary tumor of the anal canal. Although exceptionally rare, the presence of a cerebral lesion in a patient with carcinoma of the anal canal should raise the possibility of metastatic disease. Treatment decisions in patients with newly diagnosed dural-based enhancing lesions and known anal cancer should bear in mind the possibility of metastatic disease. |
| doi_str_mv | 10.1007/s11060-010-0218-5 |
| format | Article |
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A literature review identifies two cases of brain metastases from anal cancer. The authors present the case of a 63-year-old female with poorly differentiated squamous cell carcinoma of the anal canal who presented with a solitary dural-based enhancing lesion of the right parietal area. The patient underwent craniectomy and tumor resection. Histopathology confirmed the cerebral lesion to be a poorly differentiated squamous cell carcinoma, consistent with the known primary tumor of the anal canal. Although exceptionally rare, the presence of a cerebral lesion in a patient with carcinoma of the anal canal should raise the possibility of metastatic disease. 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A literature review identifies two cases of brain metastases from anal cancer. The authors present the case of a 63-year-old female with poorly differentiated squamous cell carcinoma of the anal canal who presented with a solitary dural-based enhancing lesion of the right parietal area. The patient underwent craniectomy and tumor resection. Histopathology confirmed the cerebral lesion to be a poorly differentiated squamous cell carcinoma, consistent with the known primary tumor of the anal canal. Although exceptionally rare, the presence of a cerebral lesion in a patient with carcinoma of the anal canal should raise the possibility of metastatic disease. 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| subjects | Antineoplastic Agents - therapeutic use Anus Neoplasms - pathology Anus Neoplasms - therapy Brain Neoplasms - secondary Brain Neoplasms - therapy Capecitabine Carcinoma, Squamous Cell - secondary Carcinoma, Squamous Cell - therapy Case Report Combined Modality Therapy Cranial Irradiation Deoxycytidine - analogs & derivatives Deoxycytidine - therapeutic use Fatal Outcome Female Fluorouracil - analogs & derivatives Fluorouracil - therapeutic use Humans Medicine Medicine & Public Health Middle Aged Neurology Neurosurgical Procedures Oncology Radiotherapy |
| title | Anal cancer with cerebral metastasis: a case report |
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