Novel strategies for tracing the exposure of meat cattle to illegal growth-promoters
Official monitoring of residues in cattle throughout the European Union in 2007 found
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Veröffentlicht in: | The veterinary journal (1997) 2011-07, Vol.189 (1), p.34-42 |
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container_title | The veterinary journal (1997) |
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creator | Nebbia, C. Urbani, A. Carletti, M. Gardini, G. Balbo, A. Bertarelli, D. Girolami, F. |
description | Official monitoring of residues in cattle throughout the European Union in 2007 found |
doi_str_mv | 10.1016/j.tvjl.2010.06.016 |
format | Article |
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This review summarises the published data relating to experimental and field studies performed in meat cattle, emphasising the impact of the ‘omic’ technologies and bioinformatics to discover suitable biomarkers for residue surveillance. Further research is required before any potential biomarkers can be utilised for large scale high throughput screening tests.</description><identifier>ISSN: 1090-0233</identifier><identifier>EISSN: 1532-2971</identifier><identifier>DOI: 10.1016/j.tvjl.2010.06.016</identifier><identifier>PMID: 20659808</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject><![CDATA[adrenal cortex hormones ; Adrenal Cortex Hormones - administration & dosage ; Adrenal Cortex Hormones - analysis ; Adrenergic beta-Agonists - administration & dosage ; Adrenergic beta-Agonists - analysis ; Animals ; bioinformatics ; Biomarkers ; Biomarkers - analysis ; Biomolecular techniques ; Cattle ; cattle breeding ; cost effectiveness ; Drug Approval - legislation & jurisprudence ; Drug Residues - analysis ; European Union ; field experimentation ; Gonadal Steroid Hormones - administration & dosage ; Gonadal Steroid Hormones - analysis ; Growth Hormone - administration & dosage ; Growth Hormone - analysis ; Growth Substances - administration & dosage ; Growth Substances - analysis ; Illegal growth-promoters ; meat ; Meat - analysis ; Meat cattle ; monitoring ; Official controls ; screening ; sex hormones ; Substance Abuse Detection - methods ; Substance Abuse Detection - veterinary]]></subject><ispartof>The veterinary journal (1997), 2011-07, Vol.189 (1), p.34-42</ispartof><rights>2010 Elsevier Ltd</rights><rights>Copyright © 2010 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-acbfbe058f10a979ce8aedf140b91c60e3748fc1147563f9993354a37ef0048e3</citedby><cites>FETCH-LOGICAL-c455t-acbfbe058f10a979ce8aedf140b91c60e3748fc1147563f9993354a37ef0048e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.tvjl.2010.06.016$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20659808$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nebbia, C.</creatorcontrib><creatorcontrib>Urbani, A.</creatorcontrib><creatorcontrib>Carletti, M.</creatorcontrib><creatorcontrib>Gardini, G.</creatorcontrib><creatorcontrib>Balbo, A.</creatorcontrib><creatorcontrib>Bertarelli, D.</creatorcontrib><creatorcontrib>Girolami, F.</creatorcontrib><title>Novel strategies for tracing the exposure of meat cattle to illegal growth-promoters</title><title>The veterinary journal (1997)</title><addtitle>Vet J</addtitle><description>Official monitoring of residues in cattle throughout the European Union in 2007 found <0.2% non-compliance for the use of illegal growth-promoters (GPs), including sex steroids, corticosteroids and β-agonists. There is evidence, however, that these figures may underestimate the real incidence of GP abuse in meat cattle breeding. One source of evidence arises from the introduction of new detection strategies in response to the demand for safe and wholesome food. These strategies are based on the biological effects of the different GP classes in target species, with a focus on identifying reliable and cost effective biomarkers to improve detection methods.
This review summarises the published data relating to experimental and field studies performed in meat cattle, emphasising the impact of the ‘omic’ technologies and bioinformatics to discover suitable biomarkers for residue surveillance. Further research is required before any potential biomarkers can be utilised for large scale high throughput screening tests.</description><subject>adrenal cortex hormones</subject><subject>Adrenal Cortex Hormones - administration & dosage</subject><subject>Adrenal Cortex Hormones - analysis</subject><subject>Adrenergic beta-Agonists - administration & dosage</subject><subject>Adrenergic beta-Agonists - analysis</subject><subject>Animals</subject><subject>bioinformatics</subject><subject>Biomarkers</subject><subject>Biomarkers - analysis</subject><subject>Biomolecular techniques</subject><subject>Cattle</subject><subject>cattle breeding</subject><subject>cost effectiveness</subject><subject>Drug Approval - legislation & jurisprudence</subject><subject>Drug Residues - analysis</subject><subject>European Union</subject><subject>field experimentation</subject><subject>Gonadal Steroid Hormones - administration & dosage</subject><subject>Gonadal Steroid Hormones - analysis</subject><subject>Growth Hormone - administration & dosage</subject><subject>Growth Hormone - analysis</subject><subject>Growth Substances - administration & dosage</subject><subject>Growth Substances - analysis</subject><subject>Illegal growth-promoters</subject><subject>meat</subject><subject>Meat - analysis</subject><subject>Meat cattle</subject><subject>monitoring</subject><subject>Official controls</subject><subject>screening</subject><subject>sex hormones</subject><subject>Substance Abuse Detection - methods</subject><subject>Substance Abuse Detection - veterinary</subject><issn>1090-0233</issn><issn>1532-2971</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEFvGyEQhVHVqEnd_oEeGm45rTMssLtIvVRR0kaKkkOTM8J42GCxxgHsNP8-WE57bIUGhqdvHugR8oXBnAHrzlfzsluFeQtVgG5epXfkhEneNq3q2fvag4IGWs6PycecVwCghGg_kOMWOqkGGE7I_W3cYaC5JFNw9Jipi4nWm_XrkZZHpPh7E_M2IY2OTmgKtaaUgLRE6kPA0QQ6pvhcHptNilMsmPIncuRMyPj57ZyRh6vL-4ufzc3dj-uL7zeNFVKWxtiFWyDIwTEwqlcWB4NLxwQsFLMdIO_F4Cxjopcdd0opzqUwvEcHIAbkM3J28K0vP20xFz35bDEEs8a4zVpJ0bFe8f6_5NBz1oq6V7I9kDbFnBM6vUl-MulFM9D72PVK72PX-9g1dLpKdejrm_12MeHy78ifnCtwegCcidqMyWf98Ks6SKjFVV0z8u1AYA1s5zHpbD2uLS59Qlv0Mvp__eAVuR6dWQ</recordid><startdate>20110701</startdate><enddate>20110701</enddate><creator>Nebbia, C.</creator><creator>Urbani, A.</creator><creator>Carletti, M.</creator><creator>Gardini, G.</creator><creator>Balbo, A.</creator><creator>Bertarelli, D.</creator><creator>Girolami, F.</creator><general>Elsevier Ltd</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>20110701</creationdate><title>Novel strategies for tracing the exposure of meat cattle to illegal growth-promoters</title><author>Nebbia, C. ; Urbani, A. ; Carletti, M. ; Gardini, G. ; Balbo, A. ; Bertarelli, D. ; Girolami, F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c455t-acbfbe058f10a979ce8aedf140b91c60e3748fc1147563f9993354a37ef0048e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>adrenal cortex hormones</topic><topic>Adrenal Cortex Hormones - administration & dosage</topic><topic>Adrenal Cortex Hormones - analysis</topic><topic>Adrenergic beta-Agonists - administration & dosage</topic><topic>Adrenergic beta-Agonists - analysis</topic><topic>Animals</topic><topic>bioinformatics</topic><topic>Biomarkers</topic><topic>Biomarkers - analysis</topic><topic>Biomolecular techniques</topic><topic>Cattle</topic><topic>cattle breeding</topic><topic>cost effectiveness</topic><topic>Drug Approval - legislation & jurisprudence</topic><topic>Drug Residues - analysis</topic><topic>European Union</topic><topic>field experimentation</topic><topic>Gonadal Steroid Hormones - administration & dosage</topic><topic>Gonadal Steroid Hormones - analysis</topic><topic>Growth Hormone - administration & dosage</topic><topic>Growth Hormone - analysis</topic><topic>Growth Substances - administration & dosage</topic><topic>Growth Substances - analysis</topic><topic>Illegal growth-promoters</topic><topic>meat</topic><topic>Meat - analysis</topic><topic>Meat cattle</topic><topic>monitoring</topic><topic>Official controls</topic><topic>screening</topic><topic>sex hormones</topic><topic>Substance Abuse Detection - methods</topic><topic>Substance Abuse Detection - veterinary</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nebbia, C.</creatorcontrib><creatorcontrib>Urbani, A.</creatorcontrib><creatorcontrib>Carletti, M.</creatorcontrib><creatorcontrib>Gardini, G.</creatorcontrib><creatorcontrib>Balbo, A.</creatorcontrib><creatorcontrib>Bertarelli, D.</creatorcontrib><creatorcontrib>Girolami, F.</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>The veterinary journal (1997)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nebbia, C.</au><au>Urbani, A.</au><au>Carletti, M.</au><au>Gardini, G.</au><au>Balbo, A.</au><au>Bertarelli, D.</au><au>Girolami, F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel strategies for tracing the exposure of meat cattle to illegal growth-promoters</atitle><jtitle>The veterinary journal (1997)</jtitle><addtitle>Vet J</addtitle><date>2011-07-01</date><risdate>2011</risdate><volume>189</volume><issue>1</issue><spage>34</spage><epage>42</epage><pages>34-42</pages><issn>1090-0233</issn><eissn>1532-2971</eissn><abstract>Official monitoring of residues in cattle throughout the European Union in 2007 found <0.2% non-compliance for the use of illegal growth-promoters (GPs), including sex steroids, corticosteroids and β-agonists. There is evidence, however, that these figures may underestimate the real incidence of GP abuse in meat cattle breeding. One source of evidence arises from the introduction of new detection strategies in response to the demand for safe and wholesome food. These strategies are based on the biological effects of the different GP classes in target species, with a focus on identifying reliable and cost effective biomarkers to improve detection methods.
This review summarises the published data relating to experimental and field studies performed in meat cattle, emphasising the impact of the ‘omic’ technologies and bioinformatics to discover suitable biomarkers for residue surveillance. Further research is required before any potential biomarkers can be utilised for large scale high throughput screening tests.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>20659808</pmid><doi>10.1016/j.tvjl.2010.06.016</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | adrenal cortex hormones Adrenal Cortex Hormones - administration & dosage Adrenal Cortex Hormones - analysis Adrenergic beta-Agonists - administration & dosage Adrenergic beta-Agonists - analysis Animals bioinformatics Biomarkers Biomarkers - analysis Biomolecular techniques Cattle cattle breeding cost effectiveness Drug Approval - legislation & jurisprudence Drug Residues - analysis European Union field experimentation Gonadal Steroid Hormones - administration & dosage Gonadal Steroid Hormones - analysis Growth Hormone - administration & dosage Growth Hormone - analysis Growth Substances - administration & dosage Growth Substances - analysis Illegal growth-promoters meat Meat - analysis Meat cattle monitoring Official controls screening sex hormones Substance Abuse Detection - methods Substance Abuse Detection - veterinary |
title | Novel strategies for tracing the exposure of meat cattle to illegal growth-promoters |
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