Hypertrophy of the lumbar ligamentum flavum is associated with inflammation-related TGF-β expression

Background Despite the significance of hypertrophy of the ligamentum flavum (HLF) in the disease progress of neurogenic claudication, the cellular mechanisms underlying the gradual fibrotic thickening of the ligamentum flavum remain poorly understood. The aim of our study was to get insight into the...

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Veröffentlicht in:	Acta neurochirurgica 2011, Vol.153 (1), p.134-141
Hauptverfasser:	Löhr, Mario, Hampl, Jürgen Anton, Lee, Jin Yul, Ernestus, Ralf-Ingo, Deckert, Martina, Stenzel, Werner
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Collagen - metabolism Experimental Research Extracellular Space - genetics Extracellular Space - metabolism Female Humans Hypertrophy Inflammation Mediators - metabolism Interventional Radiology Ligamentum Flavum - metabolism Ligamentum Flavum - pathology Lumbar Vertebrae - metabolism Lumbar Vertebrae - pathology Male Medicine Medicine & Public Health Middle Aged Minimally Invasive Surgery Neurology Neuroradiology Neurosurgery Spinal Stenosis - metabolism Spinal Stenosis - pathology Surgical Orthopedics Transforming Growth Factor beta - biosynthesis Transforming Growth Factor beta - genetics
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