The lactic acid stinging test predicts susceptibility to cumulative irritation caused by two lipophilic irritants

Background. Skin exposure to lipophilic irritants at workplaces is a risk factor for the development of occupational irritant hand dermatitis. Suitable lipophilic model irritants to be used in repeated irritation studies in volunteers are needed to gain a better understanding of the chemical‐depende...

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Veröffentlicht in:	Contact dermatitis 2010-12, Vol.63 (6), p.347-356
Hauptverfasser:	Schliemann, Sibylle, Antonov, Dimitar, Manegold, Nicole, Elsner, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Allergic diseases Benzene Derivatives - chemistry Benzene Derivatives - toxicity bioengineering Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Contact dermatitis cumene cumulative irritation Dermatitis, Irritant - etiology Dermatitis, Irritant - physiopathology Female Hand Humans Immunopathology irritant contact dermatitis Irritants - chemistry Irritants - toxicity Lactic Acid - pharmacology lactic acid stinging test laser Doppler flowmetry lipophilic irritants Male Medical research Medical sciences Middle Aged octane Octanes - chemistry Octanes - toxicity Patch Tests - methods Predictive Value of Tests Risk factors Skin Skin - drug effects Skin allergic diseases. Stinging insect allergies skin capacitance Solvents TEWL Time Factors Toxicology Young Adult
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