BsmI vitamin D receptor's polymorphism and bone mineral density in men and premenopausal women on long-term antiepileptic therapy

Background: Utilization of antiepileptic drugs (AEDs) has long been associated with bone deleterious effects. Furthermore, the BsmI restriction fragment polymorphism of the vitamin D receptor (VDR) has been associated with reduced bone mineral density (BMD), mostly in postmenopausal women. This stu...

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Veröffentlicht in:	European journal of neurology 2011-01, Vol.18 (1), p.93-98
Hauptverfasser:	Lambrinoudaki, I., Kaparos, G., Armeni, E., Alexandrou, A., Damaskos, C., Logothetis, E., Creatsa, M., Antoniou, A., Kouskouni, E., Triantafyllou, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon Adolescent Adult Alleles Anticonvulsants - therapeutic use Bone Density - genetics bone mineral density BsmI Calcium, Dietary Carbamazepine - analogs & derivatives Carbamazepine - therapeutic use Cross-Sectional Studies epilepsy Epilepsy - drug therapy Epilepsy - genetics Female Genotype Humans Indexing in process Male Middle Aged Piracetam - analogs & derivatives Piracetam - therapeutic use Polymorphism, Genetic Premenopause - genetics Receptors, Calcitriol - genetics Regression Analysis Statistics, Nonparametric Valproic Acid - therapeutic use VDR
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