Mesenchymal stem cells' interaction with skin: Wound-healing effect on fibroblast cells and skin tissue

ABSTRACT Mesenchymal stem cells (MSCs) are multipotent progenitor cells with the ability to secrete growth factors. Because wound healing is associated with fibroblast cells and extracellular matrix (ECM) in the dermis and epidermis, we used fibroblast cells to resolve the question of whether or not...

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Veröffentlicht in:	Wound repair and regeneration 2010-11, Vol.18 (6), p.655-661
Hauptverfasser:	Jeon, Young Keul, Jang, Yun Ho, Yoo, Dong Ryeol, Kim, Si Na, Lee, Sang Koo, Nam, Myeong Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Movement Cell Proliferation Cell survival Collagen Collagen - metabolism Culture Media, Conditioned Dermis Elastin Elastin - metabolism Enzymes Epidermis Extracellular matrix Fibroblasts Fibroblasts - metabolism Fibronectin Fibronectins - metabolism Glutathione peroxidase Glutathione Peroxidase - metabolism Growth factors In Vitro Techniques Male Matrix Metalloproteinase 1 - metabolism Mesenchymal Stromal Cells - physiology Mesenchyme mRNA Oxidative Stress Rats Rats, Sprague-Dawley Secretion Skin Skin - cytology Skin - injuries Stem cells Superoxide dismutase Superoxide Dismutase - metabolism Wound Healing
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