Relationship between TNFA, TNFB and TNFRII gene polymorphisms and outcome after unrelated hematopoietic cell transplantation in a Chinese population

This study aimed to analyze the association between cytokine gene polymorphisms and outcome following allogeneic hematopoietic SCT (allo-HSCT). A total of 138 unrelated donor/recipient pairs who underwent allo-HSCT from 2001 to 2009 were tested for TNFA-1031 (T>C), -863 (C>A), -857 (C>T), -...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2011-03, Vol.46 (3), p.400-407
Hauptverfasser:	Xiao, H W, Lai, X Y, Luo, Y, Shi, J M, Tan, Y M, He, J S, Xie, W Z, Li, L, Zhu, X L, Zhu, J J, Sun, J, Wei, G Q, Jin, L, Liu, L Z, Wu, K N, Yu, X H, Cai, Z, Lin, M F, Ye, X J, Huang, H
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/726/649 631/45/127/1220 692/699/249/1529 692/700/565/545/576/1955 Adolescent Adult Alleles Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Asian Continental Ancestry Group Biological and medical sciences Bone marrow Bone marrow, stem cells transplantation. Graft versus host reaction Cell Biology Child China Codons Cohort Studies Cytokines Donors Female Gene polymorphism Genetic aspects Genetic polymorphisms Genotype & phenotype Genotypes Graft vs Host Disease - etiology Graft vs Host Disease - genetics Graft-versus-host reaction Health aspects Hematology Hematopoietic Stem Cell Transplantation Hematopoietic stem cells Hemopoiesis Histocompatibility antigen HLA Humans Internal Medicine Lymphotoxin-alpha - genetics Male Medical sciences Medicine Medicine & Public Health Middle Aged Multivariate analysis Nucleotides original-article Physiological aspects Polymorphism Polymorphism, Genetic Polymorphism, Single Nucleotide Population studies Public Health Receptors, Tumor Necrosis Factor, Type II - genetics Risk assessment Single nucleotide polymorphisms Single-nucleotide polymorphism Stem cell transplantation Stem Cells Survival Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Treatment Outcome Tumor necrosis factor Tumor necrosis factor- alpha Tumor Necrosis Factor-alpha - genetics Young Adult
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