Kinetics of pulmonary V . hbox O 2 and femoral artery blood flow and their relationship during repeated bouts of heavy exercise

Kinetics of pulmonary V . hbox O 2 and femoral artery blood flow and their relationship during repeated bouts of heavy exercise

The mechanism that alters the pulmonary V . hbox O 2 response to heavy-intensity exercise following prior heavy exercise has been frequently ascribed to an improvement in pre-exercise blood flow (BF) or O sub(2) delivery. Interventions to improve O sub(2) delivery have rarely resulted in a similar e...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:European journal of applied physiology 2005-12, Vol.95 (5-6), p.418-430
Hauptverfasser: Endo, Masako, Okada, Yoko, Rossiter, Harry B, Ooue, Anna, Miura, Akira, Koga, Shunsaku, Fukuba, Yoshiyuki
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 430
container_issue 5-6
container_start_page 418
container_title European journal of applied physiology
container_volume 95
creator Endo, Masako
Okada, Yoko
Rossiter, Harry B
Ooue, Anna
Miura, Akira
Koga, Shunsaku
Fukuba, Yoshiyuki
description The mechanism that alters the pulmonary V . hbox O 2 response to heavy-intensity exercise following prior heavy exercise has been frequently ascribed to an improvement in pre-exercise blood flow (BF) or O sub(2) delivery. Interventions to improve O sub(2) delivery have rarely resulted in a similar enhancement of V . hbox O 2 . However, the actual limb blood flow and V . hbox O 2 dynamics in the second bout of repeated exercise remain equivocal. Seven healthy female subjects (21-32years) performed consecutive 6-min (separated by 6min of 10W exercise) bilateral knee extension (KE) exercise in a semisupine position at a work rate halfway between the lactate threshold (LT) and V . hbox O 2 peak. Femoral artery blood flow (FBF) was measured by Doppler ultrasound simultaneously with breath-by-breath V . hbox O 2 ; each protocol being repeated at least four times for precise kinetic characterization. The effective time-constant ( tau ') of the V . hbox O 2 response was reduced following prior exercise (bout 1: 61.0 plus or minus 10.5 vs. bout 2: 51.6 plus or minus 9.0s; mean plus or minus SD; P
doi_str_mv 10.1007/s00421-005-0051-2
format Article
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_954605305</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>954605305</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_9546053053</originalsourceid><addsrcrecordid>eNqNTctKxEAQHETB9fEB3vrmKWtPHrubsyiCBy_idZkkHTMymY7TM7p78teNi3gWqqiiqqCUutK41IjrG0Esc50hVj_UWX6kFros6mxV5OvjP6_rU3Um8oaIm1xvFurr0XqKthXgHqbkRvYm7OEFljA0vIMnyMH4DnoaORgHJkSa-8Yxz6Hjz0MbB7IBAjkTLXsZ7ARdCta_ztlEJlIHDad4OBnIfOyBdhRaK3ShTnrjhC5_9Vxd39893z5kU-D3RBK3o5WWnDOeOMm2rsoVVsWM_y-_AdmEWdg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>954605305</pqid></control><display><type>article</type><title>Kinetics of pulmonary V . hbox O 2 and femoral artery blood flow and their relationship during repeated bouts of heavy exercise</title><source>SpringerNature Journals</source><creator>Endo, Masako ; Okada, Yoko ; Rossiter, Harry B ; Ooue, Anna ; Miura, Akira ; Koga, Shunsaku ; Fukuba, Yoshiyuki</creator><creatorcontrib>Endo, Masako ; Okada, Yoko ; Rossiter, Harry B ; Ooue, Anna ; Miura, Akira ; Koga, Shunsaku ; Fukuba, Yoshiyuki</creatorcontrib><description>The mechanism that alters the pulmonary V . hbox O 2 response to heavy-intensity exercise following prior heavy exercise has been frequently ascribed to an improvement in pre-exercise blood flow (BF) or O sub(2) delivery. Interventions to improve O sub(2) delivery have rarely resulted in a similar enhancement of V . hbox O 2 . However, the actual limb blood flow and V . hbox O 2 dynamics in the second bout of repeated exercise remain equivocal. Seven healthy female subjects (21-32years) performed consecutive 6-min (separated by 6min of 10W exercise) bilateral knee extension (KE) exercise in a semisupine position at a work rate halfway between the lactate threshold (LT) and V . hbox O 2 peak. Femoral artery blood flow (FBF) was measured by Doppler ultrasound simultaneously with breath-by-breath V . hbox O 2 ; each protocol being repeated at least four times for precise kinetic characterization. The effective time-constant ( tau ') of the V . hbox O 2 response was reduced following prior exercise (bout 1: 61.0 plus or minus 10.5 vs. bout 2: 51.6 plus or minus 9.0s; mean plus or minus SD; P&lt;0.05), which was a result of a reduced slow component (bout 1: 16.0 plus or minus 8.0 vs. bout 2: 12.5 plus or minus 6.7 %; P&lt;0.05) and an unchanged 'primary' tau . FBF was consistently faster than V . hbox O 2 . However, there was no bout-effect on tau ' FBF (bout 1: 28.2 plus or minus 12.0 vs. bout 2: 34.2 plus or minus 8.5s). The relationship between the exercise-associated V . hbox O 2 (i.e., Delta V . hbox O 2 ) and Delta FBF was similar between bouts, with a tendency (N.S: P&gt;0.05) for Delta V . hbox O 2 / Delta hbox FBF to be increased during the transition to bout 2 rather than decreased, as hypothesized. The return of V . hbox O 2 kinetics toward first order, therefore, was associated with an 'appropriate', not enhanced, BF to the working muscles. Whether a relative prior-hyperemia in bout 2 enables a more homogeneous intramuscular distribution of BF and/or metabolic response is unclear, however, these data are consistent with events more proximal to the exercise muscle in mediating the V . hbox O 2 response during repeated heavy-intensity KE exercise.</description><identifier>ISSN: 1439-6319</identifier><identifier>EISSN: 1439-6327</identifier><identifier>DOI: 10.1007/s00421-005-0051-2</identifier><language>eng</language><ispartof>European journal of applied physiology, 2005-12, Vol.95 (5-6), p.418-430</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids></links><search><creatorcontrib>Endo, Masako</creatorcontrib><creatorcontrib>Okada, Yoko</creatorcontrib><creatorcontrib>Rossiter, Harry B</creatorcontrib><creatorcontrib>Ooue, Anna</creatorcontrib><creatorcontrib>Miura, Akira</creatorcontrib><creatorcontrib>Koga, Shunsaku</creatorcontrib><creatorcontrib>Fukuba, Yoshiyuki</creatorcontrib><title>Kinetics of pulmonary V . hbox O 2 and femoral artery blood flow and their relationship during repeated bouts of heavy exercise</title><title>European journal of applied physiology</title><description>The mechanism that alters the pulmonary V . hbox O 2 response to heavy-intensity exercise following prior heavy exercise has been frequently ascribed to an improvement in pre-exercise blood flow (BF) or O sub(2) delivery. Interventions to improve O sub(2) delivery have rarely resulted in a similar enhancement of V . hbox O 2 . However, the actual limb blood flow and V . hbox O 2 dynamics in the second bout of repeated exercise remain equivocal. Seven healthy female subjects (21-32years) performed consecutive 6-min (separated by 6min of 10W exercise) bilateral knee extension (KE) exercise in a semisupine position at a work rate halfway between the lactate threshold (LT) and V . hbox O 2 peak. Femoral artery blood flow (FBF) was measured by Doppler ultrasound simultaneously with breath-by-breath V . hbox O 2 ; each protocol being repeated at least four times for precise kinetic characterization. The effective time-constant ( tau ') of the V . hbox O 2 response was reduced following prior exercise (bout 1: 61.0 plus or minus 10.5 vs. bout 2: 51.6 plus or minus 9.0s; mean plus or minus SD; P&lt;0.05), which was a result of a reduced slow component (bout 1: 16.0 plus or minus 8.0 vs. bout 2: 12.5 plus or minus 6.7 %; P&lt;0.05) and an unchanged 'primary' tau . FBF was consistently faster than V . hbox O 2 . However, there was no bout-effect on tau ' FBF (bout 1: 28.2 plus or minus 12.0 vs. bout 2: 34.2 plus or minus 8.5s). The relationship between the exercise-associated V . hbox O 2 (i.e., Delta V . hbox O 2 ) and Delta FBF was similar between bouts, with a tendency (N.S: P&gt;0.05) for Delta V . hbox O 2 / Delta hbox FBF to be increased during the transition to bout 2 rather than decreased, as hypothesized. The return of V . hbox O 2 kinetics toward first order, therefore, was associated with an 'appropriate', not enhanced, BF to the working muscles. Whether a relative prior-hyperemia in bout 2 enables a more homogeneous intramuscular distribution of BF and/or metabolic response is unclear, however, these data are consistent with events more proximal to the exercise muscle in mediating the V . hbox O 2 response during repeated heavy-intensity KE exercise.</description><issn>1439-6319</issn><issn>1439-6327</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNqNTctKxEAQHETB9fEB3vrmKWtPHrubsyiCBy_idZkkHTMymY7TM7p78teNi3gWqqiiqqCUutK41IjrG0Esc50hVj_UWX6kFros6mxV5OvjP6_rU3Um8oaIm1xvFurr0XqKthXgHqbkRvYm7OEFljA0vIMnyMH4DnoaORgHJkSa-8Yxz6Hjz0MbB7IBAjkTLXsZ7ARdCta_ztlEJlIHDad4OBnIfOyBdhRaK3ShTnrjhC5_9Vxd39893z5kU-D3RBK3o5WWnDOeOMm2rsoVVsWM_y-_AdmEWdg</recordid><startdate>20051201</startdate><enddate>20051201</enddate><creator>Endo, Masako</creator><creator>Okada, Yoko</creator><creator>Rossiter, Harry B</creator><creator>Ooue, Anna</creator><creator>Miura, Akira</creator><creator>Koga, Shunsaku</creator><creator>Fukuba, Yoshiyuki</creator><scope>7TS</scope></search><sort><creationdate>20051201</creationdate><title>Kinetics of pulmonary V . hbox O 2 and femoral artery blood flow and their relationship during repeated bouts of heavy exercise</title><author>Endo, Masako ; Okada, Yoko ; Rossiter, Harry B ; Ooue, Anna ; Miura, Akira ; Koga, Shunsaku ; Fukuba, Yoshiyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_9546053053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Endo, Masako</creatorcontrib><creatorcontrib>Okada, Yoko</creatorcontrib><creatorcontrib>Rossiter, Harry B</creatorcontrib><creatorcontrib>Ooue, Anna</creatorcontrib><creatorcontrib>Miura, Akira</creatorcontrib><creatorcontrib>Koga, Shunsaku</creatorcontrib><creatorcontrib>Fukuba, Yoshiyuki</creatorcontrib><collection>Physical Education Index</collection><jtitle>European journal of applied physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Endo, Masako</au><au>Okada, Yoko</au><au>Rossiter, Harry B</au><au>Ooue, Anna</au><au>Miura, Akira</au><au>Koga, Shunsaku</au><au>Fukuba, Yoshiyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Kinetics of pulmonary V . hbox O 2 and femoral artery blood flow and their relationship during repeated bouts of heavy exercise</atitle><jtitle>European journal of applied physiology</jtitle><date>2005-12-01</date><risdate>2005</risdate><volume>95</volume><issue>5-6</issue><spage>418</spage><epage>430</epage><pages>418-430</pages><issn>1439-6319</issn><eissn>1439-6327</eissn><abstract>The mechanism that alters the pulmonary V . hbox O 2 response to heavy-intensity exercise following prior heavy exercise has been frequently ascribed to an improvement in pre-exercise blood flow (BF) or O sub(2) delivery. Interventions to improve O sub(2) delivery have rarely resulted in a similar enhancement of V . hbox O 2 . However, the actual limb blood flow and V . hbox O 2 dynamics in the second bout of repeated exercise remain equivocal. Seven healthy female subjects (21-32years) performed consecutive 6-min (separated by 6min of 10W exercise) bilateral knee extension (KE) exercise in a semisupine position at a work rate halfway between the lactate threshold (LT) and V . hbox O 2 peak. Femoral artery blood flow (FBF) was measured by Doppler ultrasound simultaneously with breath-by-breath V . hbox O 2 ; each protocol being repeated at least four times for precise kinetic characterization. The effective time-constant ( tau ') of the V . hbox O 2 response was reduced following prior exercise (bout 1: 61.0 plus or minus 10.5 vs. bout 2: 51.6 plus or minus 9.0s; mean plus or minus SD; P&lt;0.05), which was a result of a reduced slow component (bout 1: 16.0 plus or minus 8.0 vs. bout 2: 12.5 plus or minus 6.7 %; P&lt;0.05) and an unchanged 'primary' tau . FBF was consistently faster than V . hbox O 2 . However, there was no bout-effect on tau ' FBF (bout 1: 28.2 plus or minus 12.0 vs. bout 2: 34.2 plus or minus 8.5s). The relationship between the exercise-associated V . hbox O 2 (i.e., Delta V . hbox O 2 ) and Delta FBF was similar between bouts, with a tendency (N.S: P&gt;0.05) for Delta V . hbox O 2 / Delta hbox FBF to be increased during the transition to bout 2 rather than decreased, as hypothesized. The return of V . hbox O 2 kinetics toward first order, therefore, was associated with an 'appropriate', not enhanced, BF to the working muscles. Whether a relative prior-hyperemia in bout 2 enables a more homogeneous intramuscular distribution of BF and/or metabolic response is unclear, however, these data are consistent with events more proximal to the exercise muscle in mediating the V . hbox O 2 response during repeated heavy-intensity KE exercise.</abstract><doi>10.1007/s00421-005-0051-2</doi></addata></record>
fulltext fulltext
identifier ISSN: 1439-6319
ispartof European journal of applied physiology, 2005-12, Vol.95 (5-6), p.418-430
issn 1439-6319
1439-6327
language eng
recordid cdi_proquest_miscellaneous_954605305
source SpringerNature Journals
title Kinetics of pulmonary V . hbox O 2 and femoral artery blood flow and their relationship during repeated bouts of heavy exercise
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-14T00%3A57%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Kinetics%20of%20pulmonary%20V%20.%20hbox%20O%202%20and%20femoral%20artery%20blood%20flow%20and%20their%20relationship%20during%20repeated%20bouts%20of%20heavy%20exercise&rft.jtitle=European%20journal%20of%20applied%20physiology&rft.au=Endo,%20Masako&rft.date=2005-12-01&rft.volume=95&rft.issue=5-6&rft.spage=418&rft.epage=430&rft.pages=418-430&rft.issn=1439-6319&rft.eissn=1439-6327&rft_id=info:doi/10.1007/s00421-005-0051-2&rft_dat=%3Cproquest%3E954605305%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=954605305&rft_id=info:pmid/&rfr_iscdi=true