Corticotrophin-releasing hormone (CRH) facilitates axon outgrowth

Objective: To evaluate the role of corticotrophin-releasing hormone (CRH) in facilitating axon outgrowth. Background: Injured neural tissue is difficult to regenerate; the mechanism has not been fully understood. Methods: A rat model of spinal cord transection injury was developed. Levels of BDNF, C...

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Veröffentlicht in:	Spinal cord 2010-12, Vol.48 (12), p.850-856
Hauptverfasser:	Yuan, H, Xu, S, Wang, Y, Xu, H, Wang, C, Zhu, Q, Yang, R-K, Chen, X, Yang, P-C, Shi, X
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/1687 631/378/1687/1825 Anatomy Animals Axons - metabolism Axotomy Biological and medical sciences Biomedical and Life Sciences Biomedicine Blotting, Western Brain-Derived Neurotrophic Factor - biosynthesis Cell Communication - physiology Cerebrospinal fluid. Meninges. Spinal cord Coculture Techniques Corticotropin-Releasing Hormone - metabolism Disease Models, Animal Enzyme-Linked Immunosorbent Assay Ganglia, Spinal - physiology GPI-Linked Proteins Human Physiology Injuries of the nervous system and the skull. Diseases due to physical agents Medical sciences Microglia - metabolism Microscopy, Confocal Myelin Proteins Myelin-Associated Glycoprotein - biosynthesis Myelin-Oligodendrocyte Glycoprotein Nerve Regeneration - physiology Nervous system (semeiology, syndromes) Neurochemistry Neurology Neuropsychology Neurosciences Oligodendroglia - metabolism original-article Rats Rats, Sprague-Dawley Spinal Cord Injuries - metabolism Traumas. Diseases due to physical agents
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