The effects of low dose parathyroid hormone on lumbar vertebrae in a rat model for chronic alcohol abuse

Summary This study evaluated the hypothesis that increased bone marrow adipogenesis is coupled to decreased bone formation in rats consuming alcohol. Parathyroid hormone (PTH) increased bone formation but had no effect on marrow adiposity. We conclude that increased adiposity does not prevent the bo...

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Veröffentlicht in:	Osteoporosis international 2011-04, Vol.22 (4), p.1175-1181
Hauptverfasser:	Howe, K. S., Iwaniec, U. T., Turner, R. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictive behaviors Adipocytes Adipocytes - drug effects adipogenesis Adipose tissue Adiposity - drug effects Adult and adolescent clinical studies Alcoholism Alcoholism - physiopathology Alcoholism and acute alcohol poisoning Animals Apposition Biological and medical sciences Bone (cancellous) Bone marrow Bone Marrow - drug effects Bone Marrow - physiopathology Calories Computed tomography Diets Disease Models, Animal Diseases of the osteoarticular system Drug abuse Endocrinology Ethanol Ethanol - pharmacology Hormones Lumbar Vertebrae - diagnostic imaging Lumbar Vertebrae - drug effects Lumbar Vertebrae - physiopathology Male Medical sciences Medicine Medicine & Public Health Minerals Original Article Orthopedics Osteoblasts Osteoblasts - drug effects Osteogenesis Osteogenesis - drug effects Osteogenesis - physiology Osteoporosis Osteoporosis. Osteomalacia. Paget disease Parathyroid hormone Parathyroid Hormone - pharmacology Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Rats Rats, Sprague-Dawley Rheumatology Rodents Spine Tomography Toxicology Vertebrae X-Ray Microtomography - methods
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