Population studies of 16 bovine STR loci for forensic purposes
As a consequence of the close integration of cattle into the food chain of humans, forensically relevant cases involving cattle ( Bos taurus ) DNA analysis are common. However, scientific publications reporting the information content of the commonly used bovine short tandem repeat (STR) loci remain...
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| Veröffentlicht in: | International journal of legal medicine 2011-01, Vol.125 (1), p.111-119 |
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| creator | van de Goor, L. H. P. Koskinen, M. T. van Haeringen, W. A. |
| description | As a consequence of the close integration of cattle into the food chain of humans, forensically relevant cases involving cattle (
Bos taurus
) DNA analysis are common. However, scientific publications reporting the information content of the commonly used bovine short tandem repeat (STR) loci remains scarce. Population studies were performed for 16 polymorphic STR loci (BM1818, BM1824, BM2113, CSRM60, CSSM66, ETH3, ETH10, ETH225, HAUT27, ILSTS006, INRA023, SPS115, TGLA53, TGLA122, TGLA126, and TGLA227) including 4,162 randomly selected cattle representing 20 distinct breeds. The power of parental exclusion, expected and observed heterozygosity, probability of identity, and non-amplifying (“null”) allele frequencies were calculated. Major differences existed in the information content between different cattle breeds. The selection of 16 STR loci, partially recommended by International Society for Animal Genetics as the minimum standard needed for bovine STR typing, was sufficient for forensic analysis. Furthermore, the efficacy of the loci was assessed in assigning unknown individuals to the correct breed based on genotype data. The individual assignment tests provided excellent success in several breeds. |
| doi_str_mv | 10.1007/s00414-009-0353-8 |
| format | Article |
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Bos taurus
) DNA analysis are common. However, scientific publications reporting the information content of the commonly used bovine short tandem repeat (STR) loci remains scarce. Population studies were performed for 16 polymorphic STR loci (BM1818, BM1824, BM2113, CSRM60, CSSM66, ETH3, ETH10, ETH225, HAUT27, ILSTS006, INRA023, SPS115, TGLA53, TGLA122, TGLA126, and TGLA227) including 4,162 randomly selected cattle representing 20 distinct breeds. The power of parental exclusion, expected and observed heterozygosity, probability of identity, and non-amplifying (“null”) allele frequencies were calculated. Major differences existed in the information content between different cattle breeds. The selection of 16 STR loci, partially recommended by International Society for Animal Genetics as the minimum standard needed for bovine STR typing, was sufficient for forensic analysis. Furthermore, the efficacy of the loci was assessed in assigning unknown individuals to the correct breed based on genotype data. The individual assignment tests provided excellent success in several breeds.</description><identifier>ISSN: 0937-9827</identifier><identifier>EISSN: 1437-1596</identifier><identifier>DOI: 10.1007/s00414-009-0353-8</identifier><identifier>PMID: 19506893</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Animals ; Bos taurus ; Cattle ; Cattle - genetics ; DNA Fingerprinting ; Food chains ; Forensic Medicine ; Gene Frequency ; Genetics ; Genotype & phenotype ; Laboratories ; Medical Law ; Medicine ; Medicine & Public Health ; Polymerase Chain Reaction ; Short Communication ; Tandem Repeat Sequences</subject><ispartof>International journal of legal medicine, 2011-01, Vol.125 (1), p.111-119</ispartof><rights>Springer-Verlag 2009</rights><rights>Springer-Verlag 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c468t-e2ebfbcb7f5c64ba2e7edd876182459fca4a02b4b9c79d88423a416b818b5fff3</citedby><cites>FETCH-LOGICAL-c468t-e2ebfbcb7f5c64ba2e7edd876182459fca4a02b4b9c79d88423a416b818b5fff3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00414-009-0353-8$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00414-009-0353-8$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19506893$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van de Goor, L. H. P.</creatorcontrib><creatorcontrib>Koskinen, M. T.</creatorcontrib><creatorcontrib>van Haeringen, W. A.</creatorcontrib><title>Population studies of 16 bovine STR loci for forensic purposes</title><title>International journal of legal medicine</title><addtitle>Int J Legal Med</addtitle><addtitle>Int J Legal Med</addtitle><description>As a consequence of the close integration of cattle into the food chain of humans, forensically relevant cases involving cattle (
Bos taurus
) DNA analysis are common. However, scientific publications reporting the information content of the commonly used bovine short tandem repeat (STR) loci remains scarce. Population studies were performed for 16 polymorphic STR loci (BM1818, BM1824, BM2113, CSRM60, CSSM66, ETH3, ETH10, ETH225, HAUT27, ILSTS006, INRA023, SPS115, TGLA53, TGLA122, TGLA126, and TGLA227) including 4,162 randomly selected cattle representing 20 distinct breeds. The power of parental exclusion, expected and observed heterozygosity, probability of identity, and non-amplifying (“null”) allele frequencies were calculated. Major differences existed in the information content between different cattle breeds. The selection of 16 STR loci, partially recommended by International Society for Animal Genetics as the minimum standard needed for bovine STR typing, was sufficient for forensic analysis. Furthermore, the efficacy of the loci was assessed in assigning unknown individuals to the correct breed based on genotype data. The individual assignment tests provided excellent success in several breeds.</description><subject>Animals</subject><subject>Bos taurus</subject><subject>Cattle</subject><subject>Cattle - genetics</subject><subject>DNA Fingerprinting</subject><subject>Food chains</subject><subject>Forensic Medicine</subject><subject>Gene Frequency</subject><subject>Genetics</subject><subject>Genotype & phenotype</subject><subject>Laboratories</subject><subject>Medical Law</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Polymerase Chain Reaction</subject><subject>Short Communication</subject><subject>Tandem Repeat Sequences</subject><issn>0937-9827</issn><issn>1437-1596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkU1LxDAQhoMo7rr6A7xI8eKpmqT5vAiy-AULiq7n0KSJdOk2NWkF_70pXRAE8TDMwDzzDjMvAKcIXiII-VWEkCCSQyhzWNAiF3tgjkjBc0Ql2wdzKFMtBeYzcBTjBkLEGaeHYIYkhUzIYg6un303NGVf-zaL_VDVNmbeZYhl2n_Wrc1e1y9Z402dOR_GsG2sTdYNofPRxmNw4Mom2pNdXoC3u9v18iFfPd0_Lm9WuSFM9LnFVjttNHfUMKJLbLmtKsEZEphQ6UxJSog10dJwWQlBcFESxLRAQlPnXLEAF5NuF_zHYGOvtnU0tmnK1vohKkkJS8-g8l9SYEwpZYwn8vwXufFDaNMZIwQpp4gmCE2QCT7GYJ3qQr0tw5dCUI0mqMkElUxQowlKpJmznfCgt7b6mdh9PQF4AmJqte82_Gz-W_UbKXuQkA</recordid><startdate>20110101</startdate><enddate>20110101</enddate><creator>van de Goor, L. 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Bos taurus
) DNA analysis are common. However, scientific publications reporting the information content of the commonly used bovine short tandem repeat (STR) loci remains scarce. Population studies were performed for 16 polymorphic STR loci (BM1818, BM1824, BM2113, CSRM60, CSSM66, ETH3, ETH10, ETH225, HAUT27, ILSTS006, INRA023, SPS115, TGLA53, TGLA122, TGLA126, and TGLA227) including 4,162 randomly selected cattle representing 20 distinct breeds. The power of parental exclusion, expected and observed heterozygosity, probability of identity, and non-amplifying (“null”) allele frequencies were calculated. Major differences existed in the information content between different cattle breeds. The selection of 16 STR loci, partially recommended by International Society for Animal Genetics as the minimum standard needed for bovine STR typing, was sufficient for forensic analysis. Furthermore, the efficacy of the loci was assessed in assigning unknown individuals to the correct breed based on genotype data. The individual assignment tests provided excellent success in several breeds.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>19506893</pmid><doi>10.1007/s00414-009-0353-8</doi><tpages>9</tpages></addata></record> |
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| source | MEDLINE; Springer Nature - Complete Springer Journals; HeinOnline Law Journal Library |
| subjects | Animals Bos taurus Cattle Cattle - genetics DNA Fingerprinting Food chains Forensic Medicine Gene Frequency Genetics Genotype & phenotype Laboratories Medical Law Medicine Medicine & Public Health Polymerase Chain Reaction Short Communication Tandem Repeat Sequences |
| title | Population studies of 16 bovine STR loci for forensic purposes |
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