Skin blood flow differentially affects near-infrared spectroscopy-derived measures of muscle oxygen saturation and blood volume at rest and during dynamic leg exercise
The impact of skin blood flow changes on near-infrared spectroscopy (NIRS)-derived measures of muscle oxygen saturation (SmO 2 ) and blood volume has not been fully established. We measured SmO 2 and total hemoglobin concentration ([tHb]) responses of the right vastus lateralis during rest and dynam...
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| creator | Tew, Garry A. Ruddock, Alan D. Saxton, John M. |
| description | The impact of skin blood flow changes on near-infrared spectroscopy (NIRS)-derived measures of muscle oxygen saturation (SmO
2
) and blood volume has not been fully established. We measured SmO
2
and total hemoglobin concentration ([tHb]) responses of the right vastus lateralis during rest and dynamic knee extension exercise in ten young, healthy males. The protocol was repeated four times: twice without thigh heating for reliability, and twice with different grades of thigh heating for assessing the impact of cutaneous vasodilation on SmO
2
and Δ[tHb]. The reliability of our SmO
2
and [tHb] measurements was good. Thigh heating at 37 and 42°C caused marked increases in cutaneous vascular conductance (CVC) during rest and exercise (
P
|
| doi_str_mv | 10.1007/s00421-010-1596-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_954598095</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2489852121</sourcerecordid><originalsourceid>FETCH-LOGICAL-c498t-dd153d97a4757197c4232d9ddf158db021b68e045ed18e63a57ca3c8fa1b3ca03</originalsourceid><addsrcrecordid>eNqFkcFu1DAQhiMEoqXwAFyQhYR6CoztOLGPqIKCVIkDcI4ce7JycexgJ6V5Il4TL7u0EhLiZM_4-2fG81fVcwqvKUD3JgM0jNZAoaZCtTV7UJ3Shqu65ax7eHen6qR6kvM1AEhG5ePqhEEH0AI7rX5-_uYCGXyMlow-_iDWjSMmDIvT3m9El8gsmQTUqXZhTDqhJXkuyRSzifNWW0zupiQn1HlNmEkcybRm45HE222HgWS9rEkvLgaigz12u4l-nZDohRTN8vvBrsmFHbFb0JMzxOOO4C0m4zI-rR6N2md8djzPqq_v3325-FBffbr8ePH2qjaNkkttLRXcqk43neio6kzDOLPK2pEKaQdgdGglQiPQUokt16Izmhs5ajpwo4GfVeeHunOK39cyWD-5bNB7HTCuuVeiEUqCEv8lu5a1smGCF_LlX-R1XFMo3-ilUlSq4lOB6AEyZa854djPyU06bT2Ffu92f3C7h31c3O5Z0bw4Fl6HCe2d4o-9BXh1BHQ22hf3QlnmPccb3gFtC8cOXJ73DmC6n_Df3X8Bvw7FHA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>899189143</pqid></control><display><type>article</type><title>Skin blood flow differentially affects near-infrared spectroscopy-derived measures of muscle oxygen saturation and blood volume at rest and during dynamic leg exercise</title><source>MEDLINE</source><source>SpringerNature Complete Journals</source><creator>Tew, Garry A. ; Ruddock, Alan D. ; Saxton, John M.</creator><creatorcontrib>Tew, Garry A. ; Ruddock, Alan D. ; Saxton, John M.</creatorcontrib><description>The impact of skin blood flow changes on near-infrared spectroscopy (NIRS)-derived measures of muscle oxygen saturation (SmO
2
) and blood volume has not been fully established. We measured SmO
2
and total hemoglobin concentration ([tHb]) responses of the right vastus lateralis during rest and dynamic knee extension exercise in ten young, healthy males. The protocol was repeated four times: twice without thigh heating for reliability, and twice with different grades of thigh heating for assessing the impact of cutaneous vasodilation on SmO
2
and Δ[tHb]. The reliability of our SmO
2
and [tHb] measurements was good. Thigh heating at 37 and 42°C caused marked increases in cutaneous vascular conductance (CVC) during rest and exercise (
P
< 0.001 between each condition), and small increases in SmO
2
during rest (from 69 ± 8% to 71 ± 7% and 73 ± 6%, respectively;
P
< 0.05 between each condition), but not during exercise (e.g. 1 min exercise: 51 ± 11% vs. 51 ± 11% and 52 ± 11%, respectively;
P
> 0.05 at all time points). In contrast, heating-induced increases in %CVC
peak
were accompanied by increases in [tHb] at rest and during exercise and a decrease in Δ[tHb] during exercise (all
P
< 0.05). Our findings suggest that NIRS-derived measures of SmO
2
and blood volume are differentially affected by skin blood flow at rest and during exercise. The findings from this study should be considered in NIRS experiments where skin blood flow can change markedly (e.g. high-intensity and/or prolonged exercise).</description><identifier>ISSN: 1439-6319</identifier><identifier>EISSN: 1439-6327</identifier><identifier>DOI: 10.1007/s00421-010-1596-2</identifier><identifier>PMID: 20700602</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adult ; Biological and medical sciences ; Biomedical and Life Sciences ; Biomedicine ; Blood ; Body fat ; Cohort Studies ; Exercise - physiology ; Fundamental and applied biological sciences. Psychology ; Hemoglobin ; Human Physiology ; Humans ; Knee - blood supply ; Knee - physiology ; Lasers ; Leg - blood supply ; Leg - physiology ; Male ; Muscle, Skeletal - blood supply ; Muscle, Skeletal - metabolism ; Musculoskeletal system ; Occupational Medicine/Industrial Medicine ; Original Article ; Oxygen - analysis ; Oxygen - metabolism ; Oxygen saturation ; Quadriceps Muscle - blood supply ; Quadriceps Muscle - physiology ; Reproducibility of Results ; Skin ; Skin - blood supply ; Spectroscopy, Near-Infrared ; Spectrum analysis ; Sports Medicine ; Thigh - blood supply ; Thigh - physiology ; Vasodilation - physiology ; Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports ; Young Adult</subject><ispartof>European journal of applied physiology, 2010-11, Vol.110 (5), p.1083-1089</ispartof><rights>Springer-Verlag 2010</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c498t-dd153d97a4757197c4232d9ddf158db021b68e045ed18e63a57ca3c8fa1b3ca03</citedby><cites>FETCH-LOGICAL-c498t-dd153d97a4757197c4232d9ddf158db021b68e045ed18e63a57ca3c8fa1b3ca03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00421-010-1596-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00421-010-1596-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23437016$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20700602$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tew, Garry A.</creatorcontrib><creatorcontrib>Ruddock, Alan D.</creatorcontrib><creatorcontrib>Saxton, John M.</creatorcontrib><title>Skin blood flow differentially affects near-infrared spectroscopy-derived measures of muscle oxygen saturation and blood volume at rest and during dynamic leg exercise</title><title>European journal of applied physiology</title><addtitle>Eur J Appl Physiol</addtitle><addtitle>Eur J Appl Physiol</addtitle><description>The impact of skin blood flow changes on near-infrared spectroscopy (NIRS)-derived measures of muscle oxygen saturation (SmO
2
) and blood volume has not been fully established. We measured SmO
2
and total hemoglobin concentration ([tHb]) responses of the right vastus lateralis during rest and dynamic knee extension exercise in ten young, healthy males. The protocol was repeated four times: twice without thigh heating for reliability, and twice with different grades of thigh heating for assessing the impact of cutaneous vasodilation on SmO
2
and Δ[tHb]. The reliability of our SmO
2
and [tHb] measurements was good. Thigh heating at 37 and 42°C caused marked increases in cutaneous vascular conductance (CVC) during rest and exercise (
P
< 0.001 between each condition), and small increases in SmO
2
during rest (from 69 ± 8% to 71 ± 7% and 73 ± 6%, respectively;
P
< 0.05 between each condition), but not during exercise (e.g. 1 min exercise: 51 ± 11% vs. 51 ± 11% and 52 ± 11%, respectively;
P
> 0.05 at all time points). In contrast, heating-induced increases in %CVC
peak
were accompanied by increases in [tHb] at rest and during exercise and a decrease in Δ[tHb] during exercise (all
P
< 0.05). Our findings suggest that NIRS-derived measures of SmO
2
and blood volume are differentially affected by skin blood flow at rest and during exercise. The findings from this study should be considered in NIRS experiments where skin blood flow can change markedly (e.g. high-intensity and/or prolonged exercise).</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Blood</subject><subject>Body fat</subject><subject>Cohort Studies</subject><subject>Exercise - physiology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hemoglobin</subject><subject>Human Physiology</subject><subject>Humans</subject><subject>Knee - blood supply</subject><subject>Knee - physiology</subject><subject>Lasers</subject><subject>Leg - blood supply</subject><subject>Leg - physiology</subject><subject>Male</subject><subject>Muscle, Skeletal - blood supply</subject><subject>Muscle, Skeletal - metabolism</subject><subject>Musculoskeletal system</subject><subject>Occupational Medicine/Industrial Medicine</subject><subject>Original Article</subject><subject>Oxygen - analysis</subject><subject>Oxygen - metabolism</subject><subject>Oxygen saturation</subject><subject>Quadriceps Muscle - blood supply</subject><subject>Quadriceps Muscle - physiology</subject><subject>Reproducibility of Results</subject><subject>Skin</subject><subject>Skin - blood supply</subject><subject>Spectroscopy, Near-Infrared</subject><subject>Spectrum analysis</subject><subject>Sports Medicine</subject><subject>Thigh - blood supply</subject><subject>Thigh - physiology</subject><subject>Vasodilation - physiology</subject><subject>Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. 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Psychology</topic><topic>Hemoglobin</topic><topic>Human Physiology</topic><topic>Humans</topic><topic>Knee - blood supply</topic><topic>Knee - physiology</topic><topic>Lasers</topic><topic>Leg - blood supply</topic><topic>Leg - physiology</topic><topic>Male</topic><topic>Muscle, Skeletal - blood supply</topic><topic>Muscle, Skeletal - metabolism</topic><topic>Musculoskeletal system</topic><topic>Occupational Medicine/Industrial Medicine</topic><topic>Original Article</topic><topic>Oxygen - analysis</topic><topic>Oxygen - metabolism</topic><topic>Oxygen saturation</topic><topic>Quadriceps Muscle - blood supply</topic><topic>Quadriceps Muscle - physiology</topic><topic>Reproducibility of Results</topic><topic>Skin</topic><topic>Skin - blood supply</topic><topic>Spectroscopy, Near-Infrared</topic><topic>Spectrum analysis</topic><topic>Sports Medicine</topic><topic>Thigh - blood supply</topic><topic>Thigh - physiology</topic><topic>Vasodilation - physiology</topic><topic>Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tew, Garry A.</creatorcontrib><creatorcontrib>Ruddock, Alan D.</creatorcontrib><creatorcontrib>Saxton, John M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>Physical Education Index</collection><jtitle>European journal of applied physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tew, Garry A.</au><au>Ruddock, Alan D.</au><au>Saxton, John M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Skin blood flow differentially affects near-infrared spectroscopy-derived measures of muscle oxygen saturation and blood volume at rest and during dynamic leg exercise</atitle><jtitle>European journal of applied physiology</jtitle><stitle>Eur J Appl Physiol</stitle><addtitle>Eur J Appl Physiol</addtitle><date>2010-11-01</date><risdate>2010</risdate><volume>110</volume><issue>5</issue><spage>1083</spage><epage>1089</epage><pages>1083-1089</pages><issn>1439-6319</issn><eissn>1439-6327</eissn><abstract>The impact of skin blood flow changes on near-infrared spectroscopy (NIRS)-derived measures of muscle oxygen saturation (SmO
2
) and blood volume has not been fully established. We measured SmO
2
and total hemoglobin concentration ([tHb]) responses of the right vastus lateralis during rest and dynamic knee extension exercise in ten young, healthy males. The protocol was repeated four times: twice without thigh heating for reliability, and twice with different grades of thigh heating for assessing the impact of cutaneous vasodilation on SmO
2
and Δ[tHb]. The reliability of our SmO
2
and [tHb] measurements was good. Thigh heating at 37 and 42°C caused marked increases in cutaneous vascular conductance (CVC) during rest and exercise (
P
< 0.001 between each condition), and small increases in SmO
2
during rest (from 69 ± 8% to 71 ± 7% and 73 ± 6%, respectively;
P
< 0.05 between each condition), but not during exercise (e.g. 1 min exercise: 51 ± 11% vs. 51 ± 11% and 52 ± 11%, respectively;
P
> 0.05 at all time points). In contrast, heating-induced increases in %CVC
peak
were accompanied by increases in [tHb] at rest and during exercise and a decrease in Δ[tHb] during exercise (all
P
< 0.05). Our findings suggest that NIRS-derived measures of SmO
2
and blood volume are differentially affected by skin blood flow at rest and during exercise. The findings from this study should be considered in NIRS experiments where skin blood flow can change markedly (e.g. high-intensity and/or prolonged exercise).</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>20700602</pmid><doi>10.1007/s00421-010-1596-2</doi><tpages>7</tpages></addata></record> |
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| ispartof | European journal of applied physiology, 2010-11, Vol.110 (5), p.1083-1089 |
| issn | 1439-6319 1439-6327 |
| language | eng |
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| source | MEDLINE; SpringerNature Complete Journals |
| subjects | Adult Biological and medical sciences Biomedical and Life Sciences Biomedicine Blood Body fat Cohort Studies Exercise - physiology Fundamental and applied biological sciences. Psychology Hemoglobin Human Physiology Humans Knee - blood supply Knee - physiology Lasers Leg - blood supply Leg - physiology Male Muscle, Skeletal - blood supply Muscle, Skeletal - metabolism Musculoskeletal system Occupational Medicine/Industrial Medicine Original Article Oxygen - analysis Oxygen - metabolism Oxygen saturation Quadriceps Muscle - blood supply Quadriceps Muscle - physiology Reproducibility of Results Skin Skin - blood supply Spectroscopy, Near-Infrared Spectrum analysis Sports Medicine Thigh - blood supply Thigh - physiology Vasodilation - physiology Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports Young Adult |
| title | Skin blood flow differentially affects near-infrared spectroscopy-derived measures of muscle oxygen saturation and blood volume at rest and during dynamic leg exercise |
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