Connective Tissue Growth Factor Is Associated With a Stable Atherosclerotic Plaque Phenotype and Is Involved in Plaque Stabilization After Stroke

Carotid plaques remodel toward a more stable phenotype after stroke, but not after TIA. Connective tissue growth factor (CTGF) is involved in extracellular matrix production and is expressed in atherosclerotic plaques. We studied the role of CTGF in plaque remodeling after stroke and TIA. Atheroscle...

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Veröffentlicht in:	Stroke (1970) 2010-12, Vol.41 (12), p.2979-2981
Hauptverfasser:	LEEUWIS, Jan Willem, NGUYEN, Tri Q, THEUNISSEN, Maarten G. J, PEETERS, Wouter, GOLDSCHMEDING, Roel, PASTERKAMP, Gerard, VINK, Aryan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Atherosclerosis (general aspects, experimental research) Biological and medical sciences Biomarkers Blood and lymphatic vessels Cardiology. Vascular system Cell Proliferation Collagen - metabolism Connective Tissue Growth Factor - metabolism Endarterectomy, Carotid Extracellular Matrix - metabolism Female Humans Interleukins - metabolism Male Matrix Metalloproteinases - metabolism Medical sciences Middle Aged Myocytes, Smooth Muscle - physiology Neurology Plaque, Atherosclerotic - metabolism Plaque, Atherosclerotic - pathology Risk Factors Stroke - metabolism Stroke - pathology Vascular diseases and vascular malformations of the nervous system
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