Weight Approximation in Stroke Before Thrombolysis The WAIST-Study: A Prospective Observational Dose-Finding Study

Because of the narrow therapeutic range for thrombolysis in stroke, accurate weight-based dosing is essential for efficacy and safety. Stroke patients are frequently incapable to communicate their correct body weight (BW). Thus, dosing is often based on BW estimation, which may lead to dosing errors...

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Veröffentlicht in:	Stroke (1970) 2010-12, Vol.41 (12), p.2867-2871
Hauptverfasser:	BREUER, Lorenz, NOWE, Tim, HUTTNER, Hagen B, BLINZLER, Christian, KOLLMAR, Rainer, SCHELLINGER, Peter D, SCHWAB, Stefan, KÖHRMANN, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis of Variance Anthropometry Biological and medical sciences Body Weight - physiology Cerebral Hemorrhage - chemically induced Cerebral Hemorrhage - epidemiology Data Interpretation, Statistical Dose-Response Relationship, Drug Female Fibrinolytic Agents - administration & dosage Fibrinolytic Agents - adverse effects Fibrinolytic Agents - therapeutic use Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Injections, Intravenous Male Medical Errors Medical sciences Middle Aged Nervous system (semeiology, syndromes) Neurology Odds Ratio Prospective Studies Risk Factors Stroke - drug therapy Tissue Plasminogen Activator - administration & dosage Tissue Plasminogen Activator - adverse effects Tissue Plasminogen Activator - therapeutic use Treatment Outcome Vascular diseases and vascular malformations of the nervous system
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