Behavioral effects of subchronic inhalation of toluene in adult rats

Abstract Whereas the acute neurobehavioral effects of toluene are robust and well characterized, evidence for persistent effects of repeated exposure to this industrial solvent is less compelling. The present experiment sought to determine whether subchronic inhalation of toluene caused persistent b...

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Veröffentlicht in:	Neurotoxicology and teratology 2010-11, Vol.32 (6), p.611-619
Hauptverfasser:	Beasley, Tracey E, Evansky, Paul A, Gilbert, Mary E, Bushnell, Philip J
Format:	Artikel
Sprache:	eng
Schlagworte:	Air Pollutants - toxicity Animals Behavior, Animal - drug effects Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Conditioning, Classical - drug effects discrimination Dopamine Agonists - pharmacology Dopamine Antagonists - pharmacology Dose-Response Relationship, Drug Emergency Fear conditioning Inhalation Inhalation Exposure - adverse effects Long-term effects Male Maze Learning - drug effects Medical Education Medical sciences Motor activity Motor Activity - drug effects Neurotoxicity Organic solvent Quinpirole Raclopride Rats Rats, Long-Evans Receptors, Dopamine - metabolism Signal detection Solvents Toluene Toluene - toxicity Toxicology Vapors Visual discrimination Volatilization
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