The effect of full-mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial
Khader YS, Al Habashneh R, Al Malalheh M, Bataineh A. The effect of full‐mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial. J Periodont Res 2010; 45: 741–747. © 2010 John Wiley & Sons A/S Backgr...
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| description | Khader YS, Al Habashneh R, Al Malalheh M, Bataineh A. The effect of full‐mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial. J Periodont Res 2010; 45: 741–747. © 2010 John Wiley & Sons A/S
Background and Objective: Several studies have shown that periodontitis can complicate the severity of diabetes by worsening the degree of glycemic control. The purpose of this study was to determine the effect of full‐mouth tooth extraction on glycemic control among type 2 diabetic patients.
Material and Methods: A total of 58 patients with type 2 diabetes mellitus and advanced periodontitis who were requiring extraction of all remaining teeth were randomized consecutively into treatment (full‐mouth tooth extraction) and control groups (no treatment). Eight patients were lost to follow‐up or reported use of antibiotics, leaving 50 patients to be included in the analysis. All patients had all their remaining teeth in a hopeless condition. Relevant data were collected, and glycosylated hemoglobin (HbA1c) and fasting blood glucose levels were measured at baseline and at follow‐up times of 3 and 6 mo.
Results: At baseline, the mean (SD) HbA1c level was 8.6% (1.24) in the treatment group and 7.7% (0.87) in the control group. In the treatment group, the mean HbA1c level decreased significantly from 8.6% at baseline to 7.4% after 3 mo of denture treatment, and continued to decrease to 7.3% after 6 mo. In the control group, the mean HbA1c decreased from 7.7% at baseline to 7.5% after 3 mo, and remained almost the same after 6 mo. After adjusting for the baseline HbA1c, the mean reduction in HbA1c after 3 mo in the treatment group [1.23% (0.79)] was significantly higher than the mean reduction in the control group [0.28% (0.87)].
Conclusion: Full‐mouth tooth extraction resulted in an improvement in glycemic control among diabetic patients. Large‐scale multicentre clinical trials are needed to confirm the current evidence. |
| doi_str_mv | 10.1111/j.1600-0765.2010.01294.x |
| format | Article |
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Background and Objective: Several studies have shown that periodontitis can complicate the severity of diabetes by worsening the degree of glycemic control. The purpose of this study was to determine the effect of full‐mouth tooth extraction on glycemic control among type 2 diabetic patients.
Material and Methods: A total of 58 patients with type 2 diabetes mellitus and advanced periodontitis who were requiring extraction of all remaining teeth were randomized consecutively into treatment (full‐mouth tooth extraction) and control groups (no treatment). Eight patients were lost to follow‐up or reported use of antibiotics, leaving 50 patients to be included in the analysis. All patients had all their remaining teeth in a hopeless condition. Relevant data were collected, and glycosylated hemoglobin (HbA1c) and fasting blood glucose levels were measured at baseline and at follow‐up times of 3 and 6 mo.
Results: At baseline, the mean (SD) HbA1c level was 8.6% (1.24) in the treatment group and 7.7% (0.87) in the control group. In the treatment group, the mean HbA1c level decreased significantly from 8.6% at baseline to 7.4% after 3 mo of denture treatment, and continued to decrease to 7.3% after 6 mo. In the control group, the mean HbA1c decreased from 7.7% at baseline to 7.5% after 3 mo, and remained almost the same after 6 mo. After adjusting for the baseline HbA1c, the mean reduction in HbA1c after 3 mo in the treatment group [1.23% (0.79)] was significantly higher than the mean reduction in the control group [0.28% (0.87)].
Conclusion: Full‐mouth tooth extraction resulted in an improvement in glycemic control among diabetic patients. Large‐scale multicentre clinical trials are needed to confirm the current evidence.</description><identifier>ISSN: 0022-3484</identifier><identifier>EISSN: 1600-0765</identifier><identifier>DOI: 10.1111/j.1600-0765.2010.01294.x</identifier><identifier>PMID: 20682017</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Antibiotics ; Biological and medical sciences ; Blood ; Blood Glucose - analysis ; Chi-Square Distribution ; Clinical trials ; Data processing ; Dentistry ; Dentures ; Diabetes mellitus ; Diabetes Mellitus, Type 2 - blood ; Diabetes Mellitus, Type 2 - complications ; Diabetes Mellitus, Type 2 - metabolism ; Diabetes. Impaired glucose tolerance ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Etiopathogenesis. Screening. Investigations. Target tissue resistance ; Facial bones, jaws, teeth, parodontium: diseases, semeiology ; Fasting ; Female ; Glucose ; Glycated Hemoglobin A - analysis ; glycosolated hemoglobin ; Hemoglobin ; Humans ; Linear Models ; Male ; Medical sciences ; Middle Aged ; Multivariate Analysis ; Non tumoral diseases ; Otorhinolaryngology. Stomatology ; periodontal disease ; Periodontitis ; Periodontitis - blood ; Periodontitis - complications ; Periodontitis - surgery ; Surveys and Questionnaires ; Teeth ; Tooth Extraction ; Treatment Outcome</subject><ispartof>Journal of periodontal research, 2010-12, Vol.45 (6), p.741-747</ispartof><rights>2010 John Wiley & Sons A/S</rights><rights>2015 INIST-CNRS</rights><rights>2010 John Wiley & Sons A/S.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4194-804574370073b2f9c38527a870ed805abf4b500b920214de3746ae239f7fc24c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1600-0765.2010.01294.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1600-0765.2010.01294.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23356871$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20682017$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Khader, Y. S.</creatorcontrib><creatorcontrib>Al Habashneh, R.</creatorcontrib><creatorcontrib>Al Malalheh, M.</creatorcontrib><creatorcontrib>Bataineh, A.</creatorcontrib><title>The effect of full-mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial</title><title>Journal of periodontal research</title><addtitle>J Periodontal Res</addtitle><description>Khader YS, Al Habashneh R, Al Malalheh M, Bataineh A. The effect of full‐mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial. J Periodont Res 2010; 45: 741–747. © 2010 John Wiley & Sons A/S
Background and Objective: Several studies have shown that periodontitis can complicate the severity of diabetes by worsening the degree of glycemic control. The purpose of this study was to determine the effect of full‐mouth tooth extraction on glycemic control among type 2 diabetic patients.
Material and Methods: A total of 58 patients with type 2 diabetes mellitus and advanced periodontitis who were requiring extraction of all remaining teeth were randomized consecutively into treatment (full‐mouth tooth extraction) and control groups (no treatment). Eight patients were lost to follow‐up or reported use of antibiotics, leaving 50 patients to be included in the analysis. All patients had all their remaining teeth in a hopeless condition. Relevant data were collected, and glycosylated hemoglobin (HbA1c) and fasting blood glucose levels were measured at baseline and at follow‐up times of 3 and 6 mo.
Results: At baseline, the mean (SD) HbA1c level was 8.6% (1.24) in the treatment group and 7.7% (0.87) in the control group. In the treatment group, the mean HbA1c level decreased significantly from 8.6% at baseline to 7.4% after 3 mo of denture treatment, and continued to decrease to 7.3% after 6 mo. In the control group, the mean HbA1c decreased from 7.7% at baseline to 7.5% after 3 mo, and remained almost the same after 6 mo. After adjusting for the baseline HbA1c, the mean reduction in HbA1c after 3 mo in the treatment group [1.23% (0.79)] was significantly higher than the mean reduction in the control group [0.28% (0.87)].
Conclusion: Full‐mouth tooth extraction resulted in an improvement in glycemic control among diabetic patients. Large‐scale multicentre clinical trials are needed to confirm the current evidence.</description><subject>Antibiotics</subject><subject>Biological and medical sciences</subject><subject>Blood</subject><subject>Blood Glucose - analysis</subject><subject>Chi-Square Distribution</subject><subject>Clinical trials</subject><subject>Data processing</subject><subject>Dentistry</subject><subject>Dentures</subject><subject>Diabetes mellitus</subject><subject>Diabetes Mellitus, Type 2 - blood</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diabetes Mellitus, Type 2 - metabolism</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Etiopathogenesis. Screening. Investigations. Target tissue resistance</subject><subject>Facial bones, jaws, teeth, parodontium: diseases, semeiology</subject><subject>Fasting</subject><subject>Female</subject><subject>Glucose</subject><subject>Glycated Hemoglobin A - analysis</subject><subject>glycosolated hemoglobin</subject><subject>Hemoglobin</subject><subject>Humans</subject><subject>Linear Models</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Non tumoral diseases</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>periodontal disease</subject><subject>Periodontitis</subject><subject>Periodontitis - blood</subject><subject>Periodontitis - complications</subject><subject>Periodontitis - surgery</subject><subject>Surveys and Questionnaires</subject><subject>Teeth</subject><subject>Tooth Extraction</subject><subject>Treatment Outcome</subject><issn>0022-3484</issn><issn>1600-0765</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkt9uFCEUxidGY2v1FQw3xqtZGf4MMyZemLZWm0YTral3hGEOXVZm2AKT7vpIPqWMu67eSQgH-H7fSeCcokAVXlR5vFotqhrjEouaLwjOt7giLVtsHhTHB-FhcYwxISVlDTsqnsS4wvlci_ZxcURw3WSfOC5-Xi8BgTGgE_IGmcm5cvBTWqLkfV5hk4LSyfoR5XnrthoGq5H2YwreITX48RatVbIwpoju7WzcrgER1FvVQYKIAtxNNtjM_ZvMIOVc1gZlx1lLAGn5GikU1Nj7wf6AHmmXNa0cSsEq97R4ZJSL8GwfT4qv786vT9-XV58uPpy-vSo1q1pWNphxwajAWNCOmFbThhOhGoGhbzBXnWEdx7hrCSYV64EKVisgtDXCaMI0PSle7vKug7-bICY52KjBOTWCn6JsOeM5EW3_SwreNkJkNJPP9-TUDdDLdbCDClv5pxAZeLEHVMwvNvkXtI1_OUp53Ygqc2923L11sD3oFZZzY8iVnOsv5_rLuTHk78aQG3n5-XzeZX-589uYYHPwq_Bd1oIKLm8-XsizmteX9bcv8ob-AvLivFc</recordid><startdate>201012</startdate><enddate>201012</enddate><creator>Khader, Y. S.</creator><creator>Al Habashneh, R.</creator><creator>Al Malalheh, M.</creator><creator>Bataineh, A.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>7QP</scope></search><sort><creationdate>201012</creationdate><title>The effect of full-mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial</title><author>Khader, Y. S. ; Al Habashneh, R. ; Al Malalheh, M. ; Bataineh, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4194-804574370073b2f9c38527a870ed805abf4b500b920214de3746ae239f7fc24c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Antibiotics</topic><topic>Biological and medical sciences</topic><topic>Blood</topic><topic>Blood Glucose - analysis</topic><topic>Chi-Square Distribution</topic><topic>Clinical trials</topic><topic>Data processing</topic><topic>Dentistry</topic><topic>Dentures</topic><topic>Diabetes mellitus</topic><topic>Diabetes Mellitus, Type 2 - blood</topic><topic>Diabetes Mellitus, Type 2 - complications</topic><topic>Diabetes Mellitus, Type 2 - metabolism</topic><topic>Diabetes. Impaired glucose tolerance</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Etiopathogenesis. Screening. Investigations. Target tissue resistance</topic><topic>Facial bones, jaws, teeth, parodontium: diseases, semeiology</topic><topic>Fasting</topic><topic>Female</topic><topic>Glucose</topic><topic>Glycated Hemoglobin A - analysis</topic><topic>glycosolated hemoglobin</topic><topic>Hemoglobin</topic><topic>Humans</topic><topic>Linear Models</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Non tumoral diseases</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>periodontal disease</topic><topic>Periodontitis</topic><topic>Periodontitis - blood</topic><topic>Periodontitis - complications</topic><topic>Periodontitis - surgery</topic><topic>Surveys and Questionnaires</topic><topic>Teeth</topic><topic>Tooth Extraction</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khader, Y. S.</creatorcontrib><creatorcontrib>Al Habashneh, R.</creatorcontrib><creatorcontrib>Al Malalheh, M.</creatorcontrib><creatorcontrib>Bataineh, A.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Calcium & Calcified Tissue Abstracts</collection><jtitle>Journal of periodontal research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khader, Y. S.</au><au>Al Habashneh, R.</au><au>Al Malalheh, M.</au><au>Bataineh, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of full-mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial</atitle><jtitle>Journal of periodontal research</jtitle><addtitle>J Periodontal Res</addtitle><date>2010-12</date><risdate>2010</risdate><volume>45</volume><issue>6</issue><spage>741</spage><epage>747</epage><pages>741-747</pages><issn>0022-3484</issn><eissn>1600-0765</eissn><abstract>Khader YS, Al Habashneh R, Al Malalheh M, Bataineh A. The effect of full‐mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial. J Periodont Res 2010; 45: 741–747. © 2010 John Wiley & Sons A/S
Background and Objective: Several studies have shown that periodontitis can complicate the severity of diabetes by worsening the degree of glycemic control. The purpose of this study was to determine the effect of full‐mouth tooth extraction on glycemic control among type 2 diabetic patients.
Material and Methods: A total of 58 patients with type 2 diabetes mellitus and advanced periodontitis who were requiring extraction of all remaining teeth were randomized consecutively into treatment (full‐mouth tooth extraction) and control groups (no treatment). Eight patients were lost to follow‐up or reported use of antibiotics, leaving 50 patients to be included in the analysis. All patients had all their remaining teeth in a hopeless condition. Relevant data were collected, and glycosylated hemoglobin (HbA1c) and fasting blood glucose levels were measured at baseline and at follow‐up times of 3 and 6 mo.
Results: At baseline, the mean (SD) HbA1c level was 8.6% (1.24) in the treatment group and 7.7% (0.87) in the control group. In the treatment group, the mean HbA1c level decreased significantly from 8.6% at baseline to 7.4% after 3 mo of denture treatment, and continued to decrease to 7.3% after 6 mo. In the control group, the mean HbA1c decreased from 7.7% at baseline to 7.5% after 3 mo, and remained almost the same after 6 mo. After adjusting for the baseline HbA1c, the mean reduction in HbA1c after 3 mo in the treatment group [1.23% (0.79)] was significantly higher than the mean reduction in the control group [0.28% (0.87)].
Conclusion: Full‐mouth tooth extraction resulted in an improvement in glycemic control among diabetic patients. Large‐scale multicentre clinical trials are needed to confirm the current evidence.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>20682017</pmid><doi>10.1111/j.1600-0765.2010.01294.x</doi><tpages>7</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Antibiotics Biological and medical sciences Blood Blood Glucose - analysis Chi-Square Distribution Clinical trials Data processing Dentistry Dentures Diabetes mellitus Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - metabolism Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Facial bones, jaws, teeth, parodontium: diseases, semeiology Fasting Female Glucose Glycated Hemoglobin A - analysis glycosolated hemoglobin Hemoglobin Humans Linear Models Male Medical sciences Middle Aged Multivariate Analysis Non tumoral diseases Otorhinolaryngology. Stomatology periodontal disease Periodontitis Periodontitis - blood Periodontitis - complications Periodontitis - surgery Surveys and Questionnaires Teeth Tooth Extraction Treatment Outcome |
| title | The effect of full-mouth tooth extraction on glycemic control among patients with type 2 diabetes requiring extraction of all remaining teeth: a randomized clinical trial |
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