Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches

Abstract The blood–brain barrier (BBB) is a dynamic and complex interface between blood and the central nervous system that strictly controls the exchanges between the blood and brain compartments, therefore playing a key role in brain homeostasis and providing protection against many toxic compound...

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Veröffentlicht in:	Brain Research Reviews 2010-09, Vol.64 (2), p.328-363
Hauptverfasser:	Cardoso, Filipa Lourenço, Brites, Dora, Brito, Maria Alexandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basement membranes Biological and medical sciences Blood-Brain Barrier - anatomy & histology Blood-Brain Barrier - metabolism Blood-Brain Barrier - physiology Blood–brain barrier Brain microvascular endothelial cell Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Fundamental and applied biological sciences. Psychology Humans Intercellular junction Intercellular Junctions - genetics Intercellular Junctions - metabolism Neuroglia - physiology Neurology Neurons - physiology Neurovascular unit Signal Transduction - genetics Signal Transduction - physiology Signaling Stem-cell niche Tight Junctions - metabolism Transport system Vertebrates: nervous system and sense organs
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