pS6 Expression in Normal Renal Parenchyma, Primary Renal Cell Carcinomas and their Metastases

In cancer therapy novel concepts focus on phosphoinositide-3-kinase/protein kinase B/mammalian target of rapamycin (mTOR) inhibitors. In this context, phosphorylated S6 protein of the 40S ribosomal subunit (pS6) overexpression was previously shown to be associated with sensitivity to inhibitors of m...

Ausführliche Beschreibung