Cellular Distribution, Regulated Expression, and Functional Role of the Anorexigenic Peptide, NUCB2/Nesfatin-1, in the Testis

Nesfatin-1, product of the precursor NEFA/nucleobindin2 (NUCB2), was initially identified as anorectic hypothalamic neuropeptide, acting in a leptin-independent manner. In addition to its central role in the control of energy homeostasis, evidence has mounted recently that nesfatin-1 is also produce...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2012-04, Vol.153 (4), p.1959-1971
Hauptverfasser:	García-Galiano, D, Pineda, R, Ilhan, T, Castellano, J. M, Ruiz-Pino, F, Sánchez-Garrido, M. A, Vazquez, M. J, Sangiao-Alvarellos, S, Romero-Ruiz, A, Pinilla, L, Diéguez, C, Gaytán, F, Tena-Sempere, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Animals Biological and medical sciences Calcium-Binding Proteins - metabolism DNA-Binding Proteins - metabolism Energy balance Energy Metabolism - physiology Explants Fasting Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation Homeostasis Humans Hypothalamus Leptin Leydig cells Leydig Cells - metabolism Male Metabolism Mice Mice, Inbred C57BL Models, Animal mRNA Nerve Tissue Proteins - metabolism Neuropeptides Peptides Pituitary Progenitor cells Puberty Rats Rats, Wistar Sertoli cells Sexual Maturation - physiology Testes Testis - cytology Testis - growth & development Testis - metabolism Testosterone Testosterone - metabolism Vertebrates: endocrinology
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