Antiproliferative Acetogenins from a Uvaria sp. from the Madagascar Dry Forest

Investigation of the endemic Madagascan plant Uvaria sp. for antiproliferative activity against the A2780 ovarian cancer cell line led to the isolation of two new acetogenins. The structures of these two compounds were elucidated on the basis of analysis of their 1D and 2D NMR spectra, circular dich...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2012-03, Vol.75 (3), p.479-483
Hauptverfasser:	Dai, Yumin, Harinantenaina, Liva, Brodie, Peggy J, Callmander, Martin W, Randrianaivo, Richard, Rakotonandrasana, Stephan, Rakotobe, Etienne, Rasamison, Vincent E, Shen, Yongchun, TenDyke, Karen, Suh, Edward M, Kingston, David G. I
Format:	Artikel
Sprache:	eng
Schlagworte:	acetogenins Acetogenins - chemistry Acetogenins - isolation & purification Acetogenins - pharmacology Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology circular dichroism spectroscopy Drug Screening Assays, Antitumor dry forests Female Furans - chemistry Furans - isolation & purification Furans - pharmacology Humans lung neoplasms Madagascar mass spectrometry melanoma Molecular Structure nuclear magnetic resonance spectroscopy Nuclear Magnetic Resonance, Biomolecular ovarian neoplasms Trees Uvaria Uvaria - chemistry
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