Long-term outcome with end-stage renal disease - survival is not enough: does dialysis or kidney transplantation matter?
Patients with end-stage renal disease require renal replacement therapy with either dialysis or kidney transplantation. Survival and quality of life (QoL) after transplantation are superior to chronic dialysis. Early living donor kidney transplantation is best for patient and graft survival. Preempt...
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| Veröffentlicht in: | Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz Gesundheitsforschung, Gesundheitsschutz, 2012-04, Vol.55 (4), p.543-551 |
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| container_title | Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz |
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| creator | Schulz, K-H Thaiss, F |
| description | Patients with end-stage renal disease require renal replacement therapy with either dialysis or kidney transplantation. Survival and quality of life (QoL) after transplantation are superior to chronic dialysis. Early living donor kidney transplantation is best for patient and graft survival. Preemptive living-related kidney transplantation therefore is the best medical treatment option for these patients. Patients with end-stage renal disease suffer from multiple physical and psychological complaints. The prevalence of depressive disorders is 20-25% in this population. Studies on QoL in children after kidney transplantation show a reduced physical QoL, but an overall good psychological QoL. Alarming results of numerous studies are the high non-adherence rates in adolescents. Especially exercise interventions during dialysis and after kidney transplantation show promising results. Whether QoL of patients will improve with new approaches to immunosuppressive therapy remains to be evaluated in future studies. |
| doi_str_mv | 10.1007/s00103-012-1450-2 |
| format | Article |
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Survival and quality of life (QoL) after transplantation are superior to chronic dialysis. Early living donor kidney transplantation is best for patient and graft survival. Preemptive living-related kidney transplantation therefore is the best medical treatment option for these patients. Patients with end-stage renal disease suffer from multiple physical and psychological complaints. The prevalence of depressive disorders is 20-25% in this population. Studies on QoL in children after kidney transplantation show a reduced physical QoL, but an overall good psychological QoL. Alarming results of numerous studies are the high non-adherence rates in adolescents. Especially exercise interventions during dialysis and after kidney transplantation show promising results. 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Survival and quality of life (QoL) after transplantation are superior to chronic dialysis. Early living donor kidney transplantation is best for patient and graft survival. Preemptive living-related kidney transplantation therefore is the best medical treatment option for these patients. Patients with end-stage renal disease suffer from multiple physical and psychological complaints. The prevalence of depressive disorders is 20-25% in this population. Studies on QoL in children after kidney transplantation show a reduced physical QoL, but an overall good psychological QoL. Alarming results of numerous studies are the high non-adherence rates in adolescents. Especially exercise interventions during dialysis and after kidney transplantation show promising results. Whether QoL of patients will improve with new approaches to immunosuppressive therapy remains to be evaluated in future studies.</description><subject>Adolescent</subject><subject>Child</subject><subject>Comorbidity</subject><subject>Depressive Disorder - epidemiology</subject><subject>Exercise Therapy - utilization</subject><subject>Germany - epidemiology</subject><subject>Hemodialysis, Home - utilization</subject><subject>Humans</subject><subject>Kidney Failure, Chronic - mortality</subject><subject>Kidney Failure, Chronic - psychology</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Kidney Transplantation - utilization</subject><subject>Longitudinal Studies</subject><subject>Quality of Life</subject><subject>Survivors - statistics & numerical data</subject><subject>Treatment Outcome</subject><issn>1437-1588</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo10E1LAzEQBuAgiK3VH-BFcvMUzWc38SJS_IKCFz0v2d1pG91NapKt9t8bsJ4GZh5mhhehC0avGaXVTaKUUUEo44RJRQk_QlMmRUWY0nqCTlP6KEJpLk7QhHMpmeJyin6Wwa9JhjjgMOY2DIC_Xd5g8B1J2a4BR_C2x51LYBNggtMYd25XWi5hH3KRYVxvbnEXIBVm-30qkxDxp-s87HGO1qdtb3222QWPB5vLubszdLyyfYLzQ52h98eHt8UzWb4-vSzul2TLJM2kMY3ScsV5K7u54ZWlwCUVtGnnjKmqEsK288pI0BxaZlvVKNNpQ41qmpUWUszQ1d_ebQxfI6RcDy610JeHIIypNlIXLgwv8vIgx2aArt5GN9i4r__DEr8_qWs9</recordid><startdate>201204</startdate><enddate>201204</enddate><creator>Schulz, K-H</creator><creator>Thaiss, F</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201204</creationdate><title>Long-term outcome with end-stage renal disease - survival is not enough: does dialysis or kidney transplantation matter?</title><author>Schulz, K-H ; Thaiss, F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p140t-b9b584f22c4d6927a0e24030bc61157733ac6794e82ec1ac5b59d89095bbf8343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>ger</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Child</topic><topic>Comorbidity</topic><topic>Depressive Disorder - epidemiology</topic><topic>Exercise Therapy - utilization</topic><topic>Germany - epidemiology</topic><topic>Hemodialysis, Home - utilization</topic><topic>Humans</topic><topic>Kidney Failure, Chronic - mortality</topic><topic>Kidney Failure, Chronic - psychology</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Kidney Transplantation - utilization</topic><topic>Longitudinal Studies</topic><topic>Quality of Life</topic><topic>Survivors - statistics & numerical data</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schulz, K-H</creatorcontrib><creatorcontrib>Thaiss, F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schulz, K-H</au><au>Thaiss, F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term outcome with end-stage renal disease - survival is not enough: does dialysis or kidney transplantation matter?</atitle><jtitle>Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz</jtitle><addtitle>Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz</addtitle><date>2012-04</date><risdate>2012</risdate><volume>55</volume><issue>4</issue><spage>543</spage><epage>551</epage><pages>543-551</pages><eissn>1437-1588</eissn><abstract>Patients with end-stage renal disease require renal replacement therapy with either dialysis or kidney transplantation. Survival and quality of life (QoL) after transplantation are superior to chronic dialysis. Early living donor kidney transplantation is best for patient and graft survival. Preemptive living-related kidney transplantation therefore is the best medical treatment option for these patients. Patients with end-stage renal disease suffer from multiple physical and psychological complaints. The prevalence of depressive disorders is 20-25% in this population. Studies on QoL in children after kidney transplantation show a reduced physical QoL, but an overall good psychological QoL. Alarming results of numerous studies are the high non-adherence rates in adolescents. Especially exercise interventions during dialysis and after kidney transplantation show promising results. 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| fulltext | fulltext |
| identifier | EISSN: 1437-1588 |
| ispartof | Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 2012-04, Vol.55 (4), p.543-551 |
| issn | 1437-1588 |
| language | ger |
| recordid | cdi_proquest_miscellaneous_948890392 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Adolescent Child Comorbidity Depressive Disorder - epidemiology Exercise Therapy - utilization Germany - epidemiology Hemodialysis, Home - utilization Humans Kidney Failure, Chronic - mortality Kidney Failure, Chronic - psychology Kidney Failure, Chronic - therapy Kidney Transplantation - utilization Longitudinal Studies Quality of Life Survivors - statistics & numerical data Treatment Outcome |
| title | Long-term outcome with end-stage renal disease - survival is not enough: does dialysis or kidney transplantation matter? |
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