Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254)

Summary Objective To evaluate the clinical effectiveness of intraarticular IL-1 receptor antagonist (IL-1Ra) for anterior cruciate ligament (ACL) tear. Methods Eleven patients with acute ACL tear confirmed by magnetic resonance imaging (MRI) were randomized to receive a single intraarticular injecti...

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Veröffentlicht in:	Osteoarthritis and cartilage 2012-04, Vol.20 (4), p.271-278
Hauptverfasser:	Kraus, V.B, Birmingham, J, Stabler, T.V, Feng, S, Taylor, D.C, Moorman, C.T, Garrett, W.E, Toth, A.P
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of Daily Living Adult Anterior cruciate ligament Anterior Cruciate Ligament Injuries Biomarkers Biomarkers - metabolism Clinical trial Female Humans IL-1Ra Injections, Intra-Articular Interleukin 1 Receptor Antagonist Protein - administration & dosage Interleukin 1 Receptor Antagonist Protein - therapeutic use Joint injury Knee Injuries - complications Knee Injuries - diagnosis Knee Injuries - drug therapy Knee Injuries - rehabilitation Magnetic Resonance Imaging Male Pain - drug therapy Pain - etiology Pilot Projects Post-traumatic arthritis Quality of Life Recovery of Function Rheumatology Synovial Fluid - metabolism Trauma Severity Indices Treatment Outcome Young Adult
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