Changes in physical activity in leisure time and the risk of myocardial infarction, ischemic heart disease, and all-cause mortality
Physical activity is associated to a lower risk of mortality from all-causes and from coronary heart disease.The long-term effects of changes in physical activity on coronary heart disease are, however, less known. We examined the association between changes in leisure time physical activity and the...
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| Veröffentlicht in: | European journal of epidemiology 2012-02, Vol.27 (2), p.91-99 |
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| creator | Petersen, Christina Bjørk Grønbæk, Morten Helge, Jørn Wulff Thygesen, Lau Caspar Schnohr, Peter Tolstrup, Janne Schurmann |
| description | Physical activity is associated to a lower risk of mortality from all-causes and from coronary heart disease.The long-term effects of changes in physical activity on coronary heart disease are, however, less known. We examined the association between changes in leisure time physical activity and the risk of myocardial infarction (MI), ischemic heart disease (IHD), and all-cause mortality as well as changes in blood pressure in 4,487 men and 5,956 women in the Copenhagen City Heart Study. Physical activity was measured in 1976-1978 and 1981-1983 and participants were followed in nation-wide registers until 2009. Men who decreased physical activity by at least two levels and women who decreased by one level had a higher risk of MI relatively to an unchanged physical activity level (hazard ratio [HR] = 1.74, 95% confidence interval [95% CI]: 1.17-2.60 and HR = 1.30, 95% CI: 1.03-1.65).Similar associations were found for IHD although only significant in women. In all-cause mortality, men who increased physical activity had a lower risk and both men and women who reduced physical activity had a higher risk compared to an unchanged physical activity level. No association between changes in physical activity and blood pressure was observed. Findings from this prospective study suggest that changes in physical activity affect the risk of MI, IHD and all-cause mortality. A decrease in physical activity was associated to a higher risk of coronary heart disease. |
| doi_str_mv | 10.1007/s10654-012-9656-z |
| format | Article |
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We examined the association between changes in leisure time physical activity and the risk of myocardial infarction (MI), ischemic heart disease (IHD), and all-cause mortality as well as changes in blood pressure in 4,487 men and 5,956 women in the Copenhagen City Heart Study. Physical activity was measured in 1976-1978 and 1981-1983 and participants were followed in nation-wide registers until 2009. Men who decreased physical activity by at least two levels and women who decreased by one level had a higher risk of MI relatively to an unchanged physical activity level (hazard ratio [HR] = 1.74, 95% confidence interval [95% CI]: 1.17-2.60 and HR = 1.30, 95% CI: 1.03-1.65).Similar associations were found for IHD although only significant in women. In all-cause mortality, men who increased physical activity had a lower risk and both men and women who reduced physical activity had a higher risk compared to an unchanged physical activity level. No association between changes in physical activity and blood pressure was observed. Findings from this prospective study suggest that changes in physical activity affect the risk of MI, IHD and all-cause mortality. A decrease in physical activity was associated to a higher risk of coronary heart disease.</description><identifier>ISSN: 0393-2990</identifier><identifier>EISSN: 1573-7284</identifier><identifier>DOI: 10.1007/s10654-012-9656-z</identifier><identifier>PMID: 22311520</identifier><identifier>CODEN: EJEPE8</identifier><language>eng</language><publisher>Dordrecht: Springer</publisher><subject>Aged ; Alcohol drinking ; Biological and medical sciences ; Blood pressure ; Cardiology ; Cardiology. Vascular system ; CARDIOVASCULAR DISEASE ; Cardiovascular diseases ; Cause of Death ; Coronary artery disease ; Coronary heart disease ; Denmark ; Disease risk ; Epidemiology ; Exercise ; Female ; Heart ; Humans ; Infectious Diseases ; Leisure Activities ; Leisure time ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Men ; Middle Aged ; Miscellaneous ; Mortality ; Mortality risk ; Motor Activity ; Myocardial infarction ; Myocardial Infarction - epidemiology ; Myocardial ischemia ; Myocardial Ischemia - epidemiology ; Myocarditis. Cardiomyopathies ; Oncology ; Patient assessment ; Public Health ; Public health. Hygiene ; Public health. 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We examined the association between changes in leisure time physical activity and the risk of myocardial infarction (MI), ischemic heart disease (IHD), and all-cause mortality as well as changes in blood pressure in 4,487 men and 5,956 women in the Copenhagen City Heart Study. Physical activity was measured in 1976-1978 and 1981-1983 and participants were followed in nation-wide registers until 2009. Men who decreased physical activity by at least two levels and women who decreased by one level had a higher risk of MI relatively to an unchanged physical activity level (hazard ratio [HR] = 1.74, 95% confidence interval [95% CI]: 1.17-2.60 and HR = 1.30, 95% CI: 1.03-1.65).Similar associations were found for IHD although only significant in women. In all-cause mortality, men who increased physical activity had a lower risk and both men and women who reduced physical activity had a higher risk compared to an unchanged physical activity level. No association between changes in physical activity and blood pressure was observed. Findings from this prospective study suggest that changes in physical activity affect the risk of MI, IHD and all-cause mortality. A decrease in physical activity was associated to a higher risk of coronary heart disease.</description><subject>Aged</subject><subject>Alcohol drinking</subject><subject>Biological and medical sciences</subject><subject>Blood pressure</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>CARDIOVASCULAR DISEASE</subject><subject>Cardiovascular diseases</subject><subject>Cause of Death</subject><subject>Coronary artery disease</subject><subject>Coronary heart disease</subject><subject>Denmark</subject><subject>Disease risk</subject><subject>Epidemiology</subject><subject>Exercise</subject><subject>Female</subject><subject>Heart</subject><subject>Humans</subject><subject>Infectious Diseases</subject><subject>Leisure Activities</subject><subject>Leisure time</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Men</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Mortality</subject><subject>Mortality risk</subject><subject>Motor Activity</subject><subject>Myocardial infarction</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Myocardial ischemia</subject><subject>Myocardial Ischemia - epidemiology</subject><subject>Myocarditis. Cardiomyopathies</subject><subject>Oncology</subject><subject>Patient assessment</subject><subject>Public Health</subject><subject>Public health. Hygiene</subject><subject>Public health. 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Vascular system</topic><topic>CARDIOVASCULAR DISEASE</topic><topic>Cardiovascular diseases</topic><topic>Cause of Death</topic><topic>Coronary artery disease</topic><topic>Coronary heart disease</topic><topic>Denmark</topic><topic>Disease risk</topic><topic>Epidemiology</topic><topic>Exercise</topic><topic>Female</topic><topic>Heart</topic><topic>Humans</topic><topic>Infectious Diseases</topic><topic>Leisure Activities</topic><topic>Leisure time</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Men</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Mortality</topic><topic>Mortality risk</topic><topic>Motor Activity</topic><topic>Myocardial infarction</topic><topic>Myocardial Infarction - epidemiology</topic><topic>Myocardial ischemia</topic><topic>Myocardial Ischemia - epidemiology</topic><topic>Myocarditis. 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We examined the association between changes in leisure time physical activity and the risk of myocardial infarction (MI), ischemic heart disease (IHD), and all-cause mortality as well as changes in blood pressure in 4,487 men and 5,956 women in the Copenhagen City Heart Study. Physical activity was measured in 1976-1978 and 1981-1983 and participants were followed in nation-wide registers until 2009. Men who decreased physical activity by at least two levels and women who decreased by one level had a higher risk of MI relatively to an unchanged physical activity level (hazard ratio [HR] = 1.74, 95% confidence interval [95% CI]: 1.17-2.60 and HR = 1.30, 95% CI: 1.03-1.65).Similar associations were found for IHD although only significant in women. In all-cause mortality, men who increased physical activity had a lower risk and both men and women who reduced physical activity had a higher risk compared to an unchanged physical activity level. No association between changes in physical activity and blood pressure was observed. Findings from this prospective study suggest that changes in physical activity affect the risk of MI, IHD and all-cause mortality. A decrease in physical activity was associated to a higher risk of coronary heart disease.</abstract><cop>Dordrecht</cop><pub>Springer</pub><pmid>22311520</pmid><doi>10.1007/s10654-012-9656-z</doi><tpages>9</tpages></addata></record> |
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| subjects | Aged Alcohol drinking Biological and medical sciences Blood pressure Cardiology Cardiology. Vascular system CARDIOVASCULAR DISEASE Cardiovascular diseases Cause of Death Coronary artery disease Coronary heart disease Denmark Disease risk Epidemiology Exercise Female Heart Humans Infectious Diseases Leisure Activities Leisure time Male Medical sciences Medicine Medicine & Public Health Men Middle Aged Miscellaneous Mortality Mortality risk Motor Activity Myocardial infarction Myocardial Infarction - epidemiology Myocardial ischemia Myocardial Ischemia - epidemiology Myocarditis. Cardiomyopathies Oncology Patient assessment Public Health Public health. Hygiene Public health. Hygiene-occupational medicine Risk Assessment Risk factors Risk Reduction Behavior Surveys and Questionnaires |
| title | Changes in physical activity in leisure time and the risk of myocardial infarction, ischemic heart disease, and all-cause mortality |
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