Inflammatory phase of bone healing initiates the regenerative healing cascade

Bone healing commences with an inflammatory reaction which initiates the regenerative healing process leading in the end to reconstitution of bone. An unbalanced immune reaction during this early bone healing phase is hypothesized to disturb the healing cascade in a way that delays bone healing and...

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Veröffentlicht in:	Cell and tissue research 2012-03, Vol.347 (3), p.567-573
Hauptverfasser:	Schmidt-Bleek, Katharina, Schell, Hanna, Schulz, Norma, Hoff, Paula, Perka, Carsten, Buttgereit, Frank, Volk, Hans-Dieter, Lienau, Jasmin, Duda, Georg N
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiogenesis Angiogenesis Inducing Agents - metabolism Animals Biomarkers - metabolism Biomedical and Life Sciences Biomedicine Bone and Bones - immunology Bone and Bones - pathology Bone and Bones - physiopathology Bone and Bones - surgery Bone composition Bone healing Bone marrow Bone Marrow - pathology Bone Regeneration Cytotoxicity Cytotoxicity, Immunologic Endothelial growth factors Female Hematoma Hematoma - pathology Hematopoietic stem cells Hematopoietic Stem Cells - pathology heme Heme oxygenase (decyclizing) Human Genetics Inflammation Inflammation - pathology Lymphocyte Count Lymphocytes - pathology Lymphocytes T Molecular Medicine Osteotomy Periosteum Periosteum - pathology Periosteum - physiopathology Periosteum - surgery Proteomics Regeneration - physiology Regular Article Sheep Stem cells T cells T-Lymphocytes - pathology Vascular endothelial growth factor vascular endothelial growth factors Wound Healing
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