Identification of pharmacophore in bioactive metal complexes: Synthesis, spectroscopic characterization and application

Bacteria are amongst the most adaptable organisms on the Earth. The year 2010 was always remarkable for the article published in Lancet Infection Disease by Kumarasamy et al. and the enzyme NDM-1 which makes bacteria resist designed to kill them. Four rhodium(III) chloride complexes with Gatifloxaci...

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Veröffentlicht in:	European journal of medicinal chemistry 2012-04, Vol.50, p.149-153
Hauptverfasser:	Mehrotra, Ripul, Shukla, Satyendra N., Gaur, Pratiksha, Dubey, Archana
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antitubercular Agents - pharmacology Biological and medical sciences Cells, Cultured Coordination Complexes - chemistry Escherichia coli - drug effects Fluoroquinolones Fluoroquinolones - pharmacology Gatifloxacin Magnetic Resonance Spectroscopy Medical sciences Microbial Sensitivity Tests Molecular Structure Mycobacterium tuberculosis - drug effects Pharmacology. Drug treatments Pharmacophore Rhodium Spectrophotometry, Infrared Sulfoxide Thermodynamics
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