Ancient deuterostome origins of vertebrate brain signalling centres

Neuroectodermal signalling centres induce and pattern many novel vertebrate brain structures but are absent, or divergent, in invertebrate chordates. This has led to the idea that signalling-centre genetic programs were first assembled in stem vertebrates and potentially drove morphological innovati...

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Veröffentlicht in:	Nature (London) 2012-03, Vol.483 (7389), p.289-294
Hauptverfasser:	Pani, Ariel M., Mullarkey, Erin E., Aronowicz, Jochanan, Assimacopoulos, Stavroula, Grove, Elizabeth A., Lowe, Christopher J.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136/334/1874 631/181 631/80/86 692/698/1688/64 Animals Biological and medical sciences Biological Evolution Brain Brain - anatomy & histology Brain - embryology Brain - physiology Chordata - anatomy & histology Chordata - embryology Chordata - genetics Chordata - physiology Embryos Fibroblast Growth Factors - metabolism Fundamental and applied biological sciences. Psychology Genetic aspects Genetics of eukaryotes. Biological and molecular evolution Hedgehog Proteins - metabolism Hemichordates Humanities and Social Sciences Invertebrates Less representative or incertae sedis groups: acanthocephala, chaetognatha, gnathostomulida, lophophoria, merostomata, mesozoa, myxozoa, nematorhyncha, pararthropoda, placozoa, priapuloidea, prochordata, pycnogonida, rotifera Mice Molecular weight multidisciplinary Origin Physiological aspects Science Science (multidisciplinary) Signal Transduction Structure Vertebrates Vertebrates - anatomy & histology Vertebrates - embryology Vertebrates - genetics Vertebrates - physiology Wnt Signaling Pathway
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