Modulating immunity as a therapy for bacterial infections

Key Points Immunomodulatory therapies for the treatment of bacterial infections act on the host rather than the pathogen and are intended for use as adjunctive treatments together with conventional antimicrobial drugs, particularly in the face of increasing antibiotic resistance. Toll-like receptor...

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Veröffentlicht in:	Nature reviews. Microbiology 2012-04, Vol.10 (4), p.243-254
Hauptverfasser:	Hancock, Robert E. W., Nijnik, Anastasia, Philpott, Dana J.
Format:	Artikel
Sprache:	eng
Schlagworte:	41 631/326/41/2533 631/80/86 692/699/255/1318 692/700/565/1436/2185 Adaptive immunity Adjuvants, Immunologic Antibiotics Antibodies Antigens Antimicrobial agents Bacteria Bacterial diseases Bacterial infections Bacterial Infections - immunology Bacterial Infections - therapy Biomedical and Life Sciences Care and treatment Defense Development and progression Drug Resistance, Multiple, Bacterial Genetic aspects Health aspects Humans Immune response Immune system Immunity, Innate Immunology Immunomodulation Immunotherapy Infections Infectious Diseases Life Sciences Medical Microbiology Microbiology Molecular Targeted Therapy Nod Signaling Adaptor Proteins - immunology Nod Signaling Adaptor Proteins - metabolism Parasitology Pathogens Peptides Physiological aspects Physiology review-article Signal Transduction Toll-Like Receptors - immunology Toll-Like Receptors - metabolism Virology
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