Primary hepatic lymphoma in a patient with previous rectal adenocarcinoma: a case report and discussion of etiopathogenesis and diagnostic tools

Primary hepatic lymphoma is an extremely rare malignancy accounting for 0.016% of all cases of non-Hodgkin lymphomas. Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after ra...

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Veröffentlicht in:International journal of hematology 2012-03, Vol.95 (3), p.320-323
Hauptverfasser: Raimondo, Lucia, Ferrara, Idalucia, De Stefano, Alfonso, Cella, Chiara Alessandra, D’Armiento, Francesco Paolo, Ciancia, Giuseppe, Moretto, Roberto, De Renzo, Amalia, Carlomagno, Chiara
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container_title International journal of hematology
container_volume 95
creator Raimondo, Lucia
Ferrara, Idalucia
De Stefano, Alfonso
Cella, Chiara Alessandra
D’Armiento, Francesco Paolo
Ciancia, Giuseppe
Moretto, Roberto
De Renzo, Amalia
Carlomagno, Chiara
description Primary hepatic lymphoma is an extremely rare malignancy accounting for 0.016% of all cases of non-Hodgkin lymphomas. Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after radical treatment (neoadjuvant chemoradiotherapy and surgery) for a rectal adenocarcinoma. Abdomen ultrasound showed a single nodule in the liver, which raised the issue of differential diagnosis with a metastasis from rectal cancer. After surgical removal of the nodule, histology revealed a primary B cell, stage IE follicular non-Hodgkin lymphoma, confined to the liver; indeed, no foci of lymphoma were found elsewhere in the body.
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Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after radical treatment (neoadjuvant chemoradiotherapy and surgery) for a rectal adenocarcinoma. Abdomen ultrasound showed a single nodule in the liver, which raised the issue of differential diagnosis with a metastasis from rectal cancer. 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Myelofibrosis ; Liver ; Liver Neoplasms - diagnosis ; Liver Neoplasms - drug therapy ; Liver Neoplasms - pathology ; Lymphocytes B ; Lymphoma ; Lymphoma, B-Cell - diagnosis ; Lymphoma, B-Cell - drug therapy ; Lymphoma, B-Cell - pathology ; Malignancy ; Medical sciences ; Medicine ; Medicine &amp; Public Health ; Metastases ; Middle Aged ; Neoplasm Staging ; Neoplasms, Second Primary - diagnosis ; Neoplasms, Second Primary - drug therapy ; Neoplasms, Second Primary - pathology ; Nodules ; Oncology ; Radicals ; Rectal Neoplasms - drug therapy ; Rectal Neoplasms - pathology ; Rectum ; Stomach. Duodenum. Small intestine. Colon. Rectum. 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Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after radical treatment (neoadjuvant chemoradiotherapy and surgery) for a rectal adenocarcinoma. Abdomen ultrasound showed a single nodule in the liver, which raised the issue of differential diagnosis with a metastasis from rectal cancer. 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Myelofibrosis</subject><subject>Liver</subject><subject>Liver Neoplasms - diagnosis</subject><subject>Liver Neoplasms - drug therapy</subject><subject>Liver Neoplasms - pathology</subject><subject>Lymphocytes B</subject><subject>Lymphoma</subject><subject>Lymphoma, B-Cell - diagnosis</subject><subject>Lymphoma, B-Cell - drug therapy</subject><subject>Lymphoma, B-Cell - pathology</subject><subject>Malignancy</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Metastases</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Neoplasms, Second Primary - diagnosis</subject><subject>Neoplasms, Second Primary - drug therapy</subject><subject>Neoplasms, Second Primary - pathology</subject><subject>Nodules</subject><subject>Oncology</subject><subject>Radicals</subject><subject>Rectal Neoplasms - drug therapy</subject><subject>Rectal Neoplasms - pathology</subject><subject>Rectum</subject><subject>Stomach. 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subjects Abdomen
Adenocarcinoma
Adenocarcinoma - drug therapy
Adenocarcinoma - pathology
Biological and medical sciences
Biopsy
Case Report
Case reports
Differential diagnosis
Female
Gastroenterology. Liver. Pancreas. Abdomen
Hematologic and hematopoietic diseases
Hematology
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Liver
Liver Neoplasms - diagnosis
Liver Neoplasms - drug therapy
Liver Neoplasms - pathology
Lymphocytes B
Lymphoma
Lymphoma, B-Cell - diagnosis
Lymphoma, B-Cell - drug therapy
Lymphoma, B-Cell - pathology
Malignancy
Medical sciences
Medicine
Medicine & Public Health
Metastases
Middle Aged
Neoplasm Staging
Neoplasms, Second Primary - diagnosis
Neoplasms, Second Primary - drug therapy
Neoplasms, Second Primary - pathology
Nodules
Oncology
Radicals
Rectal Neoplasms - drug therapy
Rectal Neoplasms - pathology
Rectum
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Surgery
Treatment Outcome
Tumors
Ultrasound
title Primary hepatic lymphoma in a patient with previous rectal adenocarcinoma: a case report and discussion of etiopathogenesis and diagnostic tools
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