Primary hepatic lymphoma in a patient with previous rectal adenocarcinoma: a case report and discussion of etiopathogenesis and diagnostic tools
Primary hepatic lymphoma is an extremely rare malignancy accounting for 0.016% of all cases of non-Hodgkin lymphomas. Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after ra...
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Veröffentlicht in: | International journal of hematology 2012-03, Vol.95 (3), p.320-323 |
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creator | Raimondo, Lucia Ferrara, Idalucia De Stefano, Alfonso Cella, Chiara Alessandra D’Armiento, Francesco Paolo Ciancia, Giuseppe Moretto, Roberto De Renzo, Amalia Carlomagno, Chiara |
description | Primary hepatic lymphoma is an extremely rare malignancy accounting for 0.016% of all cases of non-Hodgkin lymphomas. Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after radical treatment (neoadjuvant chemoradiotherapy and surgery) for a rectal adenocarcinoma. Abdomen ultrasound showed a single nodule in the liver, which raised the issue of differential diagnosis with a metastasis from rectal cancer. After surgical removal of the nodule, histology revealed a primary B cell, stage IE follicular non-Hodgkin lymphoma, confined to the liver; indeed, no foci of lymphoma were found elsewhere in the body. |
doi_str_mv | 10.1007/s12185-012-1025-x |
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Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after radical treatment (neoadjuvant chemoradiotherapy and surgery) for a rectal adenocarcinoma. Abdomen ultrasound showed a single nodule in the liver, which raised the issue of differential diagnosis with a metastasis from rectal cancer. After surgical removal of the nodule, histology revealed a primary B cell, stage IE follicular non-Hodgkin lymphoma, confined to the liver; indeed, no foci of lymphoma were found elsewhere in the body.</description><identifier>ISSN: 0925-5710</identifier><identifier>EISSN: 1865-3774</identifier><identifier>DOI: 10.1007/s12185-012-1025-x</identifier><identifier>PMID: 22351247</identifier><language>eng</language><publisher>Japan: Springer Japan</publisher><subject>Abdomen ; Adenocarcinoma ; Adenocarcinoma - drug therapy ; Adenocarcinoma - pathology ; Biological and medical sciences ; Biopsy ; Case Report ; Case reports ; Differential diagnosis ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Hematologic and hematopoietic diseases ; Hematology ; Humans ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Liver ; Liver Neoplasms - diagnosis ; Liver Neoplasms - drug therapy ; Liver Neoplasms - pathology ; Lymphocytes B ; Lymphoma ; Lymphoma, B-Cell - diagnosis ; Lymphoma, B-Cell - drug therapy ; Lymphoma, B-Cell - pathology ; Malignancy ; Medical sciences ; Medicine ; Medicine & Public Health ; Metastases ; Middle Aged ; Neoplasm Staging ; Neoplasms, Second Primary - diagnosis ; Neoplasms, Second Primary - drug therapy ; Neoplasms, Second Primary - pathology ; Nodules ; Oncology ; Radicals ; Rectal Neoplasms - drug therapy ; Rectal Neoplasms - pathology ; Rectum ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus ; Surgery ; Treatment Outcome ; Tumors ; Ultrasound</subject><ispartof>International journal of hematology, 2012-03, Vol.95 (3), p.320-323</ispartof><rights>The Japanese Society of Hematology 2012</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c486t-1ee46ece25876c5c3d880d44565da65e65a2d444eba5796b3aebbee33e24d55c3</citedby><cites>FETCH-LOGICAL-c486t-1ee46ece25876c5c3d880d44565da65e65a2d444eba5796b3aebbee33e24d55c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12185-012-1025-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12185-012-1025-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25720611$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22351247$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Raimondo, Lucia</creatorcontrib><creatorcontrib>Ferrara, Idalucia</creatorcontrib><creatorcontrib>De Stefano, Alfonso</creatorcontrib><creatorcontrib>Cella, Chiara Alessandra</creatorcontrib><creatorcontrib>D’Armiento, Francesco Paolo</creatorcontrib><creatorcontrib>Ciancia, Giuseppe</creatorcontrib><creatorcontrib>Moretto, Roberto</creatorcontrib><creatorcontrib>De Renzo, Amalia</creatorcontrib><creatorcontrib>Carlomagno, Chiara</creatorcontrib><title>Primary hepatic lymphoma in a patient with previous rectal adenocarcinoma: a case report and discussion of etiopathogenesis and diagnostic tools</title><title>International journal of hematology</title><addtitle>Int J Hematol</addtitle><addtitle>Int J Hematol</addtitle><description>Primary hepatic lymphoma is an extremely rare malignancy accounting for 0.016% of all cases of non-Hodgkin lymphomas. Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after radical treatment (neoadjuvant chemoradiotherapy and surgery) for a rectal adenocarcinoma. Abdomen ultrasound showed a single nodule in the liver, which raised the issue of differential diagnosis with a metastasis from rectal cancer. After surgical removal of the nodule, histology revealed a primary B cell, stage IE follicular non-Hodgkin lymphoma, confined to the liver; indeed, no foci of lymphoma were found elsewhere in the body.</description><subject>Abdomen</subject><subject>Adenocarcinoma</subject><subject>Adenocarcinoma - drug therapy</subject><subject>Adenocarcinoma - pathology</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Case Report</subject><subject>Case reports</subject><subject>Differential diagnosis</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Hematology</subject><subject>Humans</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Liver</subject><subject>Liver Neoplasms - diagnosis</subject><subject>Liver Neoplasms - drug therapy</subject><subject>Liver Neoplasms - pathology</subject><subject>Lymphocytes B</subject><subject>Lymphoma</subject><subject>Lymphoma, B-Cell - diagnosis</subject><subject>Lymphoma, B-Cell - drug therapy</subject><subject>Lymphoma, B-Cell - pathology</subject><subject>Malignancy</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metastases</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Neoplasms, Second Primary - diagnosis</subject><subject>Neoplasms, Second Primary - drug therapy</subject><subject>Neoplasms, Second Primary - pathology</subject><subject>Nodules</subject><subject>Oncology</subject><subject>Radicals</subject><subject>Rectal Neoplasms - drug therapy</subject><subject>Rectal Neoplasms - pathology</subject><subject>Rectum</subject><subject>Stomach. 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Myelofibrosis</topic><topic>Liver</topic><topic>Liver Neoplasms - diagnosis</topic><topic>Liver Neoplasms - drug therapy</topic><topic>Liver Neoplasms - pathology</topic><topic>Lymphocytes B</topic><topic>Lymphoma</topic><topic>Lymphoma, B-Cell - diagnosis</topic><topic>Lymphoma, B-Cell - drug therapy</topic><topic>Lymphoma, B-Cell - pathology</topic><topic>Malignancy</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metastases</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>Neoplasms, Second Primary - diagnosis</topic><topic>Neoplasms, Second Primary - drug therapy</topic><topic>Neoplasms, Second Primary - pathology</topic><topic>Nodules</topic><topic>Oncology</topic><topic>Radicals</topic><topic>Rectal Neoplasms - drug therapy</topic><topic>Rectal Neoplasms - pathology</topic><topic>Rectum</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. 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Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after radical treatment (neoadjuvant chemoradiotherapy and surgery) for a rectal adenocarcinoma. Abdomen ultrasound showed a single nodule in the liver, which raised the issue of differential diagnosis with a metastasis from rectal cancer. After surgical removal of the nodule, histology revealed a primary B cell, stage IE follicular non-Hodgkin lymphoma, confined to the liver; indeed, no foci of lymphoma were found elsewhere in the body.</abstract><cop>Japan</cop><pub>Springer Japan</pub><pmid>22351247</pmid><doi>10.1007/s12185-012-1025-x</doi><tpages>4</tpages></addata></record> |
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subjects | Abdomen Adenocarcinoma Adenocarcinoma - drug therapy Adenocarcinoma - pathology Biological and medical sciences Biopsy Case Report Case reports Differential diagnosis Female Gastroenterology. Liver. Pancreas. Abdomen Hematologic and hematopoietic diseases Hematology Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Liver Liver Neoplasms - diagnosis Liver Neoplasms - drug therapy Liver Neoplasms - pathology Lymphocytes B Lymphoma Lymphoma, B-Cell - diagnosis Lymphoma, B-Cell - drug therapy Lymphoma, B-Cell - pathology Malignancy Medical sciences Medicine Medicine & Public Health Metastases Middle Aged Neoplasm Staging Neoplasms, Second Primary - diagnosis Neoplasms, Second Primary - drug therapy Neoplasms, Second Primary - pathology Nodules Oncology Radicals Rectal Neoplasms - drug therapy Rectal Neoplasms - pathology Rectum Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Surgery Treatment Outcome Tumors Ultrasound |
title | Primary hepatic lymphoma in a patient with previous rectal adenocarcinoma: a case report and discussion of etiopathogenesis and diagnostic tools |
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