Nitric oxide donor and non steroidal anti inflammatory drugs as a therapy for muscular dystrophies: Evidence from a safety study with pilot efficacy measures in adult dystrophic patients

This open-label, single centre pilot study was designed to evaluate safety and tolerability of the combination of the drugs isosorbide dinitrate, a nitric oxide donor, and ibuprofen, a non steroid anti-inflammatory drug, in a cohort of adult dystrophic patients (Duchenne, Becker and Limb-Girdle Musc...

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Veröffentlicht in:	Pharmacological research 2012-04, Vol.65 (4), p.472-479
Hauptverfasser:	D’Angelo, Maria Grazia, Gandossini, Sandra, Boneschi, Filippo Martinelli, Sciorati, Clara, Bonato, Sara, Brighina, Erika, Comi, Giacomo Pietro, Turconi, Anna Carla, Magri, Francesca, Stefanoni, Giuseppe, Brunelli, Silvia, Bresolin, Nereo, Cattaneo, Dario, Clementi, Emilio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Anti-inflammatory drug Female Humans Ibuprofen - therapeutic use Isosorbide Dinitrate - therapeutic use Male Middle Aged Muscular dystrophies Muscular Dystrophies - drug therapy Nitric oxide donor Nitric Oxide Donors - therapeutic use Pharmacological treatment Safety Treatment Outcome Young Adult
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