Effects of brown alga, Ecklonia cava on glucose and lipid metabolism in C57BL/KsJ-db/db mice, a model of type 2 diabetes mellitus

► We investigated the anti-diabetic effects of Ecklonia cava in db/db mice. ► Dieckol rich extract of E.cava (AG-dieckol) was compared with agent, rosiglitazone. ► AG-dieckol exerts a beneficial effect on hepatic glucose and lipid metabolism. Recently, there has been a growing interest in alternativ...

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Veröffentlicht in:	Food and chemical toxicology 2012-03, Vol.50 (3-4), p.575-582
Hauptverfasser:	Lee, Seung-Hong, Min, Kwan-Hee, Han, Ji-Sook, Lee, Dae-Ho, Park, Deok-Bae, Jung, Won-Kyo, Park, Pyo-Jam, Jeon, Byong-Tae, Kim, Se-Kwon, Jeon, You-Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	alternative medicine Animals Anti-diabetic antioxidants Biological and medical sciences blood blood glucose C57BL/KsJ-db/db mice Chromatography, High Pressure Liquid Diabetes Mellitus, Type 2 - metabolism Diabetes. Impaired glucose tolerance Disease Models, Animal Eckloniacava Endocrine pancreas. Apud cells (diseases) Endocrinopathies enzyme activity Etiopathogenesis. Screening. Investigations. Target tissue resistance glucokinase glucose Glucose - metabolism Glucose regulating enzyme glucose tolerance glucose-6-phosphatase Glycated Hemoglobin - metabolism glycemic effect glycosylation hemoglobin insulin Insulin - blood Lipid Metabolism Lipid Peroxidation lipids Medical sciences Mice Mice, Inbred C57BL noninsulin-dependent diabetes mellitus Phaeophyceae - metabolism Phaeophycophyta Plasma insulin thiobarbituric acid-reactive substances Toxicology
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