Late Antibody-Mediated Rejection After Heart . Transplantation Following the Development of De Novo Donor-Specific Human Leukocyte Antigen Antibody

Antibody-mediated rejection (AMR) is an important problem after heart transplantation. Most cases seem to occur in sensitized recipients with preformed donor-specific human leukocyte antigen antibody (DSA) early after transplantation. Few data exist on AMR in patients who form de novo DSA. We descri...

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Veröffentlicht in:	Transplantation 2012-03, Vol.93 (6), p.650-656
Hauptverfasser:	HODGES, Aidan M, LYSTER, Haifa, MCDERMOTT, Anne, RICE, Alexandra J, SMITH, John D, ROSE, Marlene L, BANNER, Nicholas R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antibodies - immunology Antibodies, Monoclonal, Murine-Derived - therapeutic use Biological and medical sciences Boronic Acids - therapeutic use Bortezomib Cohort Studies Data processing Female Fundamental and applied biological sciences. Psychology Fundamental immunology Graft rejection Graft Rejection - epidemiology Graft Rejection - immunology Heart diseases Heart transplantation Heart Transplantation - immunology Heart Transplantation - mortality Histocompatibility antigen HLA HLA Antigens - immunology Humans Immunoglobulins Immunoglobulins, Intravenous - therapeutic use Incidence Intravenous administration Kaplan-Meier Estimate Lymph nodes Lymph Nodes - radiation effects Male Medical sciences Middle Aged Pyrazines - therapeutic use Radiation Retrospective Studies Rituximab Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Survival Survival Rate Time Factors Tissue Donors Tissue, organ and graft immunology Treatment Outcome
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