A comparative study of the use of powder X-ray diffraction, Raman and near infrared spectroscopy for quantification of binary polymorphic mixtures of piracetam

Diffraction and spectroscopic methods were evaluated for quantitative analysis of binary powder mixtures of FII(6.403) and FIII(6.525) piracetam. The two polymorphs of piracetam could be distinguished using powder X-ray diffraction (PXRD), Raman and near-infrared (NIR) spectroscopy. The results demo...

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Veröffentlicht in:Journal of pharmaceutical and biomedical analysis 2012-04, Vol.63, p.80-86
Hauptverfasser: Croker, Denise M., Hennigan, Michelle C., Maher, Anthony, Hu, Yun, Ryder, Alan G., Hodnett, Benjamin K.
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Sprache:eng
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