Suppressive effect of enzymatically modified isoquercitrin on phenobarbital-induced liver tumor promotion in rats

To investigate the effect of enzymatically modified isoquercitrin (EMIQ) on hepatocellular tumor promotion induced by phenobarbital (PB), male rats were administered a single intraperitoneal injection of 200 mg/kg N -diethylnitrosamine (DEN) and then fed with a diet containing PB (500 ppm) for 8 we...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of toxicology 2011-11, Vol.85 (11), p.1475-1484
Hauptverfasser:	Morita, Reiko, Shimamoto, Keisuke, Ishii, Yuji, Kuwata, Kazunori, Ogawa, Bun-ichiro, Imaoka, Masako, Hayashi, Shim-mo, Suzuki, Kazuhiko, Shibutani, Makoto, Mitsumori, Kunitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticarcinogenic Agents - pharmacology Anticonvulsants. Antiepileptics. Antiparkinson agents Antioxidants Aryl Hydrocarbon Hydroxylases - analysis Aryl Hydrocarbon Hydroxylases - metabolism ATP-Binding Cassette Transporters - analysis ATP-Binding Cassette Transporters - metabolism Biological and medical sciences Biomedical and Life Sciences Biomedicine Carcinogens Diethylnitrosamine - toxicity Drinking Water - chemistry Environmental Health Enzymes Gastroenterology. Liver. Pancreas. Abdomen Genotoxicity and Carcinogenicity Glutathione Transferase - metabolism Hepatectomy Liver - cytology Liver - drug effects Liver cancer Liver Neoplasms, Experimental - chemically induced Liver Neoplasms, Experimental - metabolism Liver Neoplasms, Experimental - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Neuropharmacology Occupational Medicine/Industrial Medicine Oxidative stress Oxidative Stress - drug effects Pharmacology. Drug treatments Pharmacology/Toxicology Phenobarbital - toxicity Quercetin - analogs & derivatives Quercetin - pharmacology Rats Rats, Inbred F344 Reactive Oxygen Species - metabolism Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors Receptors, Cytoplasmic and Nuclear - metabolism RNA, Messenger - metabolism Rodents Steroid Hydroxylases - analysis Steroid Hydroxylases - metabolism Toxicology Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!