Kynurenines in Parkinson’s disease: therapeutic perspectives

Parkinson’s disease (PD) is a chronic progressive neurodegenerative disorder the pathomechanism of which is not yet fully known. With regard to the molecular mechanism of development of the disease, oxidative stress/mitochondrial impairment, glutamate excitotoxicity and neuroinflammation are certain...

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Veröffentlicht in:	Journal of Neural Transmission 2012-02, Vol.119 (2), p.275-283
Hauptverfasser:	Zádori, Dénes, Klivényi, Péter, Toldi, József, Fülöp, Ferenc, Vécsei, László
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Neurosciences Excitotoxicity Genetics and Immunology - Review article Glutamic acid Humans Inflammation Kynurenine - metabolism Kynurenine - therapeutic use Medicine Medicine & Public Health Metabolism Mitochondria Molecular modelling Movement disorders Neurodegenerative diseases Neurology Neuroprotection Neuroprotective Agents - metabolism Neuroprotective Agents - therapeutic use Neurosciences Oxidative stress Parkinson Disease - drug therapy Parkinson Disease - etiology Parkinson Disease - metabolism Parkinson's disease Psychiatry Therapeutic applications Tryptophan
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