Age-related changes in the effects of 5-hydroxytryptamine on substantia gelatinosa neurons of the trigeminal subnucleus caudalis

► Hyperpolarization was the major response in SG neurons in response to 5-HT application. ► Percentage of SG neurons showing hyperpolarization to 5-HT was higher in immature. ► Amplitude of 5-HT-induced hyperpolarization decreased with increasing postnatal age. ► Postnatal age of 3weeks is a critica...

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Veröffentlicht in:	Neuroscience letters 2012-02, Vol.510 (2), p.78-81
Hauptverfasser:	Park, Seon Ah, Yang, Eun Ju, Han, Seong Kyu, Park, Soo Joung
Format:	Artikel
Sprache:	eng
Schlagworte:	5-hydroxytryptamine Aging Animals Gramicidin Gramicidin-perforated patch clamp Male Membrane Potentials Mice Neurons - drug effects Neurons - physiology Patch-Clamp Techniques Postnatal age Serotonin - pharmacology Substantia gelatinosa Substantia Gelatinosa - cytology Substantia Gelatinosa - drug effects Substantia Gelatinosa - physiology Trigeminal Caudal Nucleus - cytology Trigeminal Caudal Nucleus - drug effects Trigeminal subnucleus caudalis
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