Heterogeneity of Microbubble Accumulation: A Novel Approach to Discriminate Between Well-Differentiated Hepatocellular Carcinomas and Regenerative Nodules

Abstract This prospective study aimed to elucidate the possibility of differentiating well-differentiated hepatocellular carcinoma (wHCC) from regenerative nodule (RN) on the basis of the heterogeneity of microbubble accumulation. Intensity analysis was conducted on early-phase and late-phase (60 s...

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Veröffentlicht in:	Ultrasound in medicine & biology 2012-03, Vol.38 (3), p.383-388
Hauptverfasser:	Maruyama, Hitoshi, Takahashi, Masanori, Sekimoto, Tadashi, Kamesaki, Hidehiro, Shimada, Taro, Kanai, Fumihiko, Yokosuka, Osamu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Carcinoma, Hepatocellular - diagnostic imaging Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Cell Differentiation Contrast agent Contrast Media - pharmacokinetics Diagnosis, Differential Female Ferric Compounds - pharmacokinetics Gastroenterology. Liver. Pancreas. Abdomen Hepatocellular carcinoma Humans Investigative techniques, diagnostic techniques (general aspects) Iron - pharmacokinetics Liver Cirrhosis - diagnostic imaging Liver Cirrhosis - metabolism Liver Cirrhosis - pathology Liver Neoplasms - diagnostic imaging Liver Neoplasms - metabolism Liver Neoplasms - pathology Liver Regeneration - physiology Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Metabolic Clearance Rate Microbubbles Middle Aged Oxides - pharmacokinetics Radiology Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Regenerative nodule Reproducibility of Results Sensitivity and Specificity Tissue Distribution Tumors Ultrasonography Ultrasound
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