Agmatine protects against scopolamine-induced water maze performance impairment and hippocampal ERK and Akt inactivation

Cholinergic brain activity plays a significant role in memory. Scopolamine a muscarinic cholinergic antagonist is known to induce impairment in Morris water maze performance, the task which is mainly dependent on the hippocampus. It is suggested that hippocampal ERK and Akt activation play roles in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuropharmacology 2012-04, Vol.62 (5-6), p.2018-2023
Hauptverfasser:	Moosavi, Maryam, Yadollahi Khales, Golnaz, Abbasi, Leila, Zarifkar, Asadollah, Rastegar, Karim
Format:	Artikel
Sprache:	eng
Schlagworte:	Agmatine Agmatine - pharmacology Akt Animals ERK Hippocampus Hippocampus - drug effects Hippocampus - metabolism Learning Male MAP Kinase Signaling System - drug effects MAP Kinase Signaling System - physiology Maze Learning - drug effects Memory - drug effects Muscarinic Antagonists - pharmacology Proto-Oncogene Proteins c-akt - metabolism Rats Rats, Sprague-Dawley Scopolamine Scopolamine Hydrobromide - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!