On the selective detection of duplex deoxyribonucleic acids by 2,1,3-benzothiadiazole fluorophores

A series of 4,7-pi-extended 2,1,3-benzothiadiazoles (BTDs) with different molecular architectures, in particular, the organic dyes based on the 4-(arylethynyl)-7-(4-methoxy)-2,1,3-benzothiazole skeleton, can be used at very low concentrations (down to 10 microM) to detect DNA at 1 ppm in phosphate b...

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Veröffentlicht in:	Molecular bioSystems 2010-01, Vol.6 (6), p.967-975
Hauptverfasser:	Neto, Brenno A D, Lapis, Alexandre A M, Mancilha, Fabiana S, Batista, Jr, Eraldo L, Netz, Paulo A, Rominger, Frank, Basso, Luiz A, Santos, Diógenes S, Dupont, Jaïrton
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - chemistry Actins - genetics Binding Sites DNA - chemistry DNA - genetics Fluorescent Dyes - chemistry Humans Kinetics Models, Molecular Molecular Structure Nucleic Acid Conformation Polymerase Chain Reaction Reproducibility of Results Spectrometry, Fluorescence - methods Thiadiazoles - chemistry
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